Neuroblastoma: Patient info on symptoms, diagnosis and treatment options - PowerPoint PPT Presentation

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Neuroblastoma: Patient info on symptoms, diagnosis and treatment options

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Neuroblastoma is a rare disease in which a solid tumour caused by uncontrolled or abnormal cell growth is formed by special nerve cells called neuroblasts. – PowerPoint PPT presentation

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Title: Neuroblastoma: Patient info on symptoms, diagnosis and treatment options


1
NEUROBLASTOMA
  • Information on symptoms, diagnosis and treatment
    options

2
INTRODUCTION TO NEUROBLASTOMA
  • Cancer of the sympathetic nervous system which
    affects approximately 600 children a year and the
    average age of diagnosis is 3 yrs.
  • Stage IV Neuroblastoma is very aggressive and
    chances of survival are 30. NB has one of the
    highest rates of relapse among any cancers, and
    when it does come back, chances of survival are
    5

3
SING AND SYMPTOMS OF NEUROBLASTOMA
  • Signs and symptoms of neuroblastoma vary
    depending on what part of the body is affected.
    Symptoms of neuroblastoma in the abdomen are
  • Abdominal pain
  • A mass under the skin that isn't tender when
    touched
  • Changes in bowel habits, such as diarrhoea
  • Swelling in the legs

4
SING AND SYMPTOMS OF NEUROBLASTOMA
  • Symptoms of neuroblastoma in the chest are
  • Wheezing
  • Chest pain
  • Drooping eyelids and unequal pupil size
  • Enlarged liver
  • Fatigue

5
SING AND SYMPTOMS OF NEUROBLASTOMA
  • Other signs of neuroblastoma include 
  • Lumps of tissue under the skin
  • Eyeballs that seem to protrude from the sockets
  • Dark circles, similar to bruises, around the eyes
  • Back pain
  • Unexplained weight loss
  • Bone pain

6
TESTS AND DIAGNOSIS OF NEUROBLASTOMA
  • If your doctor suspects neuroblastoma, he may
    suggest the following tests and procedures to
    diagnose neuroblastoma 
  • Full body check-up Your child's doctor conducts
    a physical exam to check out any signs and
    symptoms.
  • Urine and blood tests These tests may identify
    the cause of any signs and symptoms your child is
    experiencing. Urine tests may be used to check
    for high levels of certain chemicals that result
    from the neuroblastoma cells producing
    excess catecholamine.

7
TESTS AND DIAGNOSIS OF NEUROBLASTOMA
  • Imaging tests Imaging tests such as X-ray,
    ultrasound, computerized tomography (CT)
    scan, metaiodobenzylguanidine (MIBG) scan and
    magnetic resonance imaging (MRI) may reveal a
    mass that can indicate a tumour.
  • Removing a sample of tissue for testing If a
    mass is found, your child's doctor may want to
    remove a sample of the tissue for laboratory
    testing which is medically known as biopsy. This
    helps the doctor devise an individualized
    treatment plan.
  • Removing a sample of bone marrow for
    testing Your child may also undergo bone marrow
    biopsy and bone marrow aspiration procedures to
    see if neuroblastoma has spread to the bone
    marrow.

8
TREATMENT OPTIONS FOR NEUROBLASTOMA 
  • The doctors are very selective in choosing the
    treatment plan because it can affect your childs
    prognosis. There are various treatment options
    for neuroblastoma, including
  • Surgery Oncologists use various surgical tools
    to remove cancer cells. In children with low-risk
    neuroblastoma, surgery to remove the tumour may
    be the only treatment needed.
  • Chemotherapy Chemotherapy uses chemicals to
    destroy cancer cells. This therapy attacks
    rapidly growing cells in the body, including
    cancer cells. Children with moderate
    neuroblastoma often receive a combination of
    chemotherapy drugs before surgery.

9
TREATMENT OPTIONS FOR NEUROBLASTOMA 
  • Radiation therapy Radiation therapy uses
    high-energy beams to execute cancer cells.
    Children with low to moderate risk of
    neuroblastoma may receive radiation therapy if
    surgery and chemotherapy haven't been helpful.
  • Stem cell transplant Children with high-risk
    neuroblastoma may receive a transplant using
    their own blood stem cells.
  • Immunotherapy This therapy uses drugs that work
    by stimulating your body's immune system to
    help fight cancer cells.

10
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