Creative Biolabs - PowerPoint PPT Presentation

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Creative Biolabs

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Title: Creative Biolabs


1
Creative Biolabs
A Helper in Your Research
Creative Biolabs is the leading custom
service provider that has
extensive experience in various antibody
production and engineering
fields. Our service portfolio includes
mouse and rat monoclonal antibody
production using hybridoma technology,
human, monkey, rabbit,
chicken, dog, llama and camel monoclonal
antibody production using
various antibody library technologies 
  • www.creative-biolabs.com

2
24 Hour Support
Products and Services 1. Antibody
Sequencing....................
...................................2 2.
Hybridoma Platform.
..3 3. Phage Display Antibody Library
Services....4 4. De
Novo Antibody Sequencing Services
...5 5. Anti-idiotype Antibody
Production Services6
6. Nanobodies
.7
1
www.creative-biolabs.com
1
1
3
24 Hour Support
Hybridoma Platform
Creative Biolabs provides a full range of
services in custom polyclonal and monoclonal
antibody production from gene expression or
peptide synthesis to antibody purification and
labeling. We have the capacity of producing
antibodies in either research quantities or in
large scale for diagnostic industry. We do
epitope prediction, peptide synthesize, protein
expression, polyclonal or monoclonal antibody
production as well as antibody purification from
cell culture, ascites fluid or whole serum.
www.creative-biolabs.com


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Phage Display Antibody Library
Services
Phage display is a laboratory technique for the
study of proteinprotein, proteinpeptide, and
proteinDNA interactions that uses bacteriophages
to connect proteins with the genetic information
that encodes them. 
Phage Display Library Construction
We are professional in construction of various
phage display libraries, including cDNA libraries
Monoclonal Chicken Antibody Production
Together with partners who are leading scientists
in monoclonal chicken IgY antibody field offers
the
Creative BioLabs is a leading service provider
that focuses on phage display technology
Internalizing Antibody Screening
Creative BioLabs offers a unique yeast display
technology UltraTM, for the
www.creative-biolabs.com
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5
24 Hour Support
Brief Introductioon of De Novo Antibody Sequencing
Creative Biolabs is gladly to show a series of
unrivalled De Novo Antibody Sequencing services,
which have been developed based on our next
generation antibody sequencing platform using the
proprietary
Sequencing of the V and J and C segments by DASS
The V and J and C gene segments of antibodies are
available in public databases (germline
sequences, see figure 1). However, during the
maturation of an antibody
De Novo Sequencing of the CDR3 Region
While the CDR3 of the light chain is mostly
encoded by the germline sequences, the CDR3 of
the heavy chain is usually not available in
databases
www.creative-biolabs.com
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6
24 Hour Support
Anti-idiotype Antibody Production Services
In addition to mouse and rat hybridoma production
methods, we have phage display immune antibody
library construction
Creative Biolabs provides unparalleled custom
Anti-Idiotypic Antibody (Anti-ID Abs) Production
and downstream assay services to support your
study, preclinical and clinical trials and the
development of monoclonal antibody drugs. 
Applications
Antibody drug Pharmacokinetic/pharmacodynamics
(PK/PD) studies the anti-ID capture Sandwich
ELISA and anti-ID antibody bridging Antibody
drug Immunogenicity (Immune Response, IR)
studies Preclinical research of therapeutic
antibodies
Creative Biolabs is professional in developing
highly specific, high affinity monoclonal
antibodies from various species
www.creative-biolabs.com
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7
24 Hour Support
Cat Product Name Abbr
NAB-L101 Recombinant Anti-Pig AMY2 Nanobody Recombinant Anti-AMY2 Nanobody
NAB-L111 Recombinant Anti-Human GH1 Nanobody Recombinant Anti-GH1 Nanobody
CSC-P0037 Recombinant Anti-Human PD1 Nanobody Anti-PD1 Nanobody
Bio-similar Cell Lines
Advantages of Nanobodies
Together with Creative Biomart, Creative Biolabs
is the pioneer and undisputed global leader in
the rapidly emerging market for biosimilars, also
known as follow-on biologics (or
biopharmaceuticals). We have developed a range of
biosimilar stable cell lines using our
proprietary gene
High production yield. Minimal size Great
stabilityReversible refoldingOutstanding
solubility in aqueous solutions Specifically
recognize unique epitopes with subnanomolar
affinity
Products like Anti-EGFR Nanobody and Anti-Rnase A
Nanobody are also available
www.creative-biolabs.com
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THANK YOU !
Candy Swift Creative Biolabs
Email contacta_at_creative-biolabs.com Address
45-16 Ramsey Road, Shirley, NY
11967, USA Tel 1-631-871-5806
9
Dong H. Chen Chief Scientific Officer Creative
Biolabs
Email contacta_at_creative-biolabs.com Address
45-16 Ramsey Road, Shirley, NY 11967, USA Tel
1-631-871-5806
10
Email contacta_at_creative-biolabs.com Address
45-16 Ramsey Road, Shirley, NY 11967, USA Tel
1-631-871-5806
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