Stem Cell & Platelet Rich Plasma Therapy

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An Introduction to Stem Cells and Platelet Rich
Plasma
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If the potential of stem cell research is
realized, it would mean an end to the suffering
of millions of people. If stem cell research
succeeds, there isnt a person in the country who
wont benefit, or know someone who will -
Michael J. Fox
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Stem Cell History
1961 Till McCulloch establish the foundation
for stem cell science. 1998 Researchers Extract
the first stem cells from human embryos 2001
President Bush restricts federal funding for
embryonic stem- cell research 2002 California
Validate and Legalizes Stem Cell Research 2009
President Obama Reverses George W. Bushs 2001
Executive Order 2011 Pope hails potential of
adult stem cell research 2013 Human Liver Created
from Stem Cells
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What is a Stem Cell?
- A cell that can continuously divide and make
copies of itself -A cell that can differentiate
into other tissue
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Types of Stem Cells

• EMBRYONIC
• Derived from blastocyst
• Pluripotent
• Ethical issue arise from this source

• ADULT
• Derived from cord blood, placenta, or adult
  tissues
• Multipotent
• No ethical issue from this source

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CLINICell Uses Adult Stem Cells
-Stem cells are harvested from patient
themselves. -Adult stem cell sources are
typically in skin, fat, bone marrow, brain and
other organs. -Not all stem cells are the
same. -Different Stem Cells for Different
Functions.
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CLINICell Applications with Stem Cells
-CLINICell uses bone marrow derived stem cells
for its orthopedic applications. The stem cell
type used is a MSC or marrow stromal cell. -This
cell type has the ability to replace and become
bone, fat, muscle, and other tissue types. -MSC
stem cell have a immuno-regulatory
property. -MSC are non tumor forming cells
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PRP vs Stem Cell

• PRP is NOT stem cells
• PRP is platelet rich plasma. This biological
  medicine elicits a healing response.
• PRP stimulates native cells and native stem
  cells to repair when administered.

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Platelet Rich Plasma

• CLINICell concentrates platelets 4x for an potent
  formula
• PRP includes- Plasma, Platelets and Growth
  Factors
• PRP can be used for many applications such as
  cosmetic benefits when places in skin, healing
  of wounds, and treatment of many orthopedic
  injuries
• Growth Factors signal native cells to perform
  specific tasks like growing, dividing, or
  telling stem cell to become a certain type of
  cell like a bone cell if needed.

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Similarities Between Stem Cells and PRP

• Elicit a Healing response
• Tell Native Cells to heal and proliferate (grow
  in number)
• Immuno-regulatory
• Can come from your own body
• Natural Mechanism for healing

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Differences Between Stem Cells and PRP

• STEM CELL
• -Cell that can turn into other cell types
• -Can continuously renew
• - Can replace lost cells by dividing and
  differentiating into the cell type needed

• PRP
• Cell already differentiate into the fate of a
  platelet
• Limited number of cell division
• Doesn'tt directly replace lost cells but
  promotes healing in the area targeted

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Science has presented us with a hope called
stem-cell research, which may provide our
scientists with answers that have so long been
beyond our grasp -Nancy Reagan