Title: Therapeutic Class Overview: Treating Refractory Hematological Malignancies
1(No Transcript)
2Report THERAPEUTIC CLASS OVERVIEW TREATING
REFRACTORY HEMATOLOGICAL MALIGNANCIES
Report Insights
- Targeting unmet needs in the treatment of cancer
or hematological malignancies through innovative
drug development strategies have witnessed
favorable outcomes - Over the past decade, Proteasome inhibitor,
Velcade (bortezomib) and the immunomodulatory
drugs - Thalomid (thalidomide) and Revlimid
(lenalidomide) have become the cornerstone of
treatment for patients with Multiple Myeloma (MM)
resulting in improved survival - However, eventually all patients relapse and new
treatment options for Relapsed/ Refractory
Multiple Myeloma (RRMM) are required to further
improve survival and quality of life of this
group of patients
3Report THERAPEUTIC CLASS OVERVIEW TREATING
REFRACTORY HEMATOLOGICAL MALIGNANCIES
Report Insights (Continued)
- Two new drugs have successfully fulfilled this
need - POMALYST/ IMNOVID (pomalidomide - POM) and
Kyprolis (carfilzomib-CFZ) - A similar scenario is expected to unfold in the
treatment of Recurrent/ Refractory MDS (RR-MDS,
High-Risk MDS), and Relapsed/ Refractory AML (R/R
AML) - Innovative approach to treating unmet need has
been handsomely rewarded in the past through
in-licensing or outright acquisition of the
mature or nascent product or innovator company at
a premium
4Report THERAPEUTIC CLASS OVERVIEW TREATING
REFRACTORY HEMATOLOGICAL MALIGNANCIES
Report Coverage
- Overview of the approved therapies for RRMM,
NDMM, AML, MDS, unmet need and limitations of the
current SOC for relapsed and refractory patients - Competition and commercial opportunity in
pursuing these therapy areas - Comprehensive list of the early and late stage
drugs in the clinic, their MoA and the companies
developing them
5Report THERAPEUTIC CLASS OVERVIEW TREATING
REFRACTORY HEMATOLOGICAL MALIGNANCIES
Table of Contents
- Executive Summary
- Disease Overview MDS and AML
- Current Standard of Care MDS and AML
- Unmet Need AML
- Late-Stage pipeline Targeting High-Risk or R/R
MDS AND R/R AML - Late-Stage pipeline Targeting 1st-line Lower Risk
MD - Key Milestones of Drugs For RRMDS/RRAML in
2014-2015 - Launch Timeline and Commercial Opportunity of
Late-Stage Pipeline (RR MDS and RR AML) - Drivers of MA/Licensing Deals in MDS/AML
6Report THERAPEUTIC CLASS OVERVIEW TREATING
REFRACTORY HEMATOLOGICAL MALIGNANCIES
Report Details
- Publish date Feb 22, 2014
- Number of slides 43
- Geographic coverage Global
- Available format PDF, CD, Hardcopy
- Price for Single User License USD 1,500
- Price for Site License USD 3,003
- Price for Global User License USD 4,503
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