The Microbial World and You

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The Microbial World and You

• Microorganisms (microbes) are too small to be
  seen with the unaided
• eye, yet are closely associated with our lives.
• Ecological role
• Commercial uses
• Agents of infectious disease (pathogens)

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Milestones in Microbiology

• Antoni Van Leeuvenhoek
• Edward Jenner
• Louis Pasteur
• Joseph Lister
• Robert Koch
• Paul Ehrlich- theory of immunity
• Alexander Fleming

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The First Microscope
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Proof of Biogenesis and Germ Theory
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The Discovery of Antibiotics
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Antibiotics are selectively toxic to bacteria
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Normal Microbiota

• In the mouth- Lactobacillus,
• Streptococcus
• On the skin- Staphylococci
• Large numbers in digestive tract, including
• E. coli
• Enterobacter
• Klebsiella
• Lactobacillus
• Proteus

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Microbes and Our Immune System

• The immune system of the human body has the
  ability to block out, remove, and destroy
  pathogens through various mechanisms
• Resistance
• Susceptibility
• Vaccines

Phagocytosis
Cytolysis
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Emerging Infectious Diseases (EIDs)

• West Nile encephalitis
• Hantavirus pulmonary syndrome
• Ebola hemorrhagic fever
• AIDS
• Factors Contributing to the emergence of EIDs?

Ebola Virus