Smallpox Vaccine Logistics: Distribution, Storage and Security

1
Smallpox Vaccine LogisticsDistribution, Storage
and Security

• WVDHHR/BPH
• US Department of Health and Human Services
• Centers for Disease Control and Prevention
• December 2002 / January 2003

2
Smallpox Vaccine Logistics Distribution,
Storage and Security

• Learning Objectives
• Describe how the smallpox vaccine will be ordered
  and shipped
• Describe the support to be provided by the
  National Pharmaceutical Stockpile
• Describe the storage and handling requirements
  for the smallpox vaccine

3
National Pharmaceutical Stockpile (NPS) Concept
of Operations

• Provide rapid delivery of a broad spectrum of
  support for an ill-defined threat in the early
  hours of an event
• Provide large shipments of specific material when
  a threat is known
• Provide technical assistance to receive and
  distribute NPS material during an event

4
NPS Response Options

• Broad Spectrum Support
• 12-hour Push Packages
• Specific Item Support
• Vendor Managed Inventory (VMI)
• Vaccines
• Buying Power/Surge Capacity

5
Distribution

• Vaccine is a licensed product and all ancillary
  support will be in the kit
• Each kit provides the capability to inoculate
  85-90 persons

6
What Do the Shipments Contain?

• Vaccine
• Diluents for vaccines that must be reconstituted
  (1 vial per every vial of vaccine)
• Bifurcated needles
• Transfer needles (1 needle for every vial of
  diluent)
• Package insert
• Lot number stickers

7
What Needs to be Acquired Locally

• Non-latex gloves
• Waterless hand cleanser
• Chux pad
• 2 X 2 gauze pads, plus cloth tape or paper tape
• Semi-permeable bandages
• Needle (21G or smaller)

8
What Needs to be Acquired Locally

• Zip lock plastic bags (to provide vaccinated
  persons with a supply of gauze pads, tape and
  bandages)
• Sharps containers
• Medical waste bags
• Bleach/spray bottle
• NOTE DO NOT procure/use alcohol or alcohol
  wipes as alcohol inactivates the vaccine

9
Vaccine Handling

• Cold Chain must be constant during distribution
• Temperature logging is required to validate that
  35 - 46 F (2-8 C) was maintained during
  movement
• Vaccine kits will be shipped in approved shipping
  containers with cold packs and temperature
  monitor
• Temperature monitor must be read as soon as
  vaccine arrives

10
Vaccine Handling

• West Virginia State Police have primary
  responsibility for security transporting
  vaccine to local/regional sites
• State Immunization Program staff will contact
  State Police for transportation of vaccine kits

11
Vaccine Handling

• Regional/local sites must designate
• Point of Contact (primary alternate)
• Name, title, address, phone, fax directions
• Delivery Site address directions
• Number of vaccination doses needed
• Desired delivery date of vaccine kits

12
Vaccine Handling

• Cold Chain must be constant during
  redistribution
• Temperature logging is required to validate that
  35 - 46 F (2-8 C) was maintained during
  movement
• Temperature monitor must be checked as soon as
  vaccine arrives

13
Storage

• All kits must be maintained at 35 -
  46 F (2-8 C)
• Proper refrigeration must be in place at point of
  delivery
• A temperature reading log must be maintained on
  the refrigeration system
• Check/record storage temperature at least 2 times
  per day

14
Security Issues

• Code of Federal Regulations must be followed
  (21CFR)
• Fixed storage facilities
• Controlled access to both facility and the
  storage system
• Surveillance (video) and/or security staff

15
Reminders

• Vaccine should NEVER be frozen
• Normal storage temperature is 35 - 46 F
  (2-8 C)
• AFTER reconstitution, vaccine
• Must be used within 60 days
• Maintained at 35 - 46 F (2-8 C)

16
For More Information

• West Virginia Immunization Program
• Jeff Neccuzi, Program Manager
• 304-558-6426 OR 304-558-2188
• 800-642-3634

17
For More Information

• National Pharmaceutical Stockpile
• Telephone [phone]
• Email NPS_PPT_at_cdc.gov

18
For More Information

• CDC Smallpox website
• www.cdc.gov/smallpox
• National Immunization Program website
• www.cdc.gov/nip