Stats 11, Winter 2004

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Stats 11, Winter 2004

• Experimental Design
• Jan 9, 2004

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London Cholera Outbreak, 1854

• Cholera kills quickly
• Primary symptom is severe diarrhea
• Modern treatment involves an IV to provide
  hydration
• Competing Theories for transmission air vs
  water (germs). Air was the predominant view.

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Golden Square, Sept 1854

• Unusually intense, deadly outbreak
• 500 deaths in just a few days
• Local panic made neighbors flee
• John Snow, a physician, believed cholera spread
  through polluted water supplies

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Is this definitive "proof"?
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Same picture, but with daily deaths
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Aside quarterly aggregates
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Fiscal Year aggregates
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Calendar Year aggregate
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Water compnies
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This area was fed by two water companies
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Deathrate less where clean water
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Current medical mystery

• Sudan's Luckless Children, Locked in Land of Nod,
  NY Times, Sept 22, 2003
• Mysterious ailment among some children of Sudan
• Nod, don't grow fully, die in late teens
• Theories fly bite, poison, contaminated food

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References found on

• http//www.ph.ucla.edu/epi/snow.html