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Outlasts,Outperforms,Outnumbers
Also Sprach Zarathustra-Eumir Deodato, Prelude
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Table of Contents

• The Silverlon Advantage slide 3
• The Negative Pressure Innovation slides 4-5
• What Silverlon Has
  slides 6-7
• How To Use slides 8-10
• Five Case Studies slides 11-22
• 90 Day Value Analysis slide 23-24
• One Year Value Analysis Projection slides 25-27
• Savings Calculator hospital slide 28
• Savings Calculator home health slide 29
• Contact Information slide 30

3
The Silverlon Advantage

• Silverlon is the most cost effective silver
  product on the market and is the most versatile.
• Silverlon can be rinsed to remove excess exudate
  and reapplied for up to 7 day use.

4
Silverlon Negative Pressure Dressings Award
Winning Innovation

• Combine Silverlon NPD with NPWT
• Accelerates Healing Potential.
• Proven in over 300 patient trials to enhance and
  accelerate granulation and wound closure by 20
  to 40 vs. Conventional protocols.
• Reduces Overall Cost of NPWT.
• Wounds heal quicker, saving rental charges, kit
  costs, and nursing time.
• Lowers Infection.
• Proven in over 300 patient trials to lower the
  risk of the media re-infecting the wound bed.

5
Silverlon Negative Pressure DressingsAward
Winning Innovation

• Combine Silverlon NPD with NPWT (Continued)
• Reduces Foam Sticking to the Wound.
• Silverlon not only reduces the incidence of
  foam adhering to the granulation bed, but it also
  eliminates the need to pick the foam out of the
  wound.
• Safe and Easy to Use.
• Silverlon is not known to interact with any
  drug and is bactericidal to all clinically
  relevant pathogens. It will not shed metallic
  silver into tissue, nor will it tattoo or stain
  the skin.

6
Silverlon Negative Pressure DressingsClinical
Investigations
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Silverlon Negative Pressure DressingsSustained
Strength Easy to Use
8
Silverlon Negative Pressure DressingsSimple
Technique Means Easy to Use
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Silverlon Negative Pressure Dressings

• Professional Guidelines For Use
• Moisten dressing with sterile or clean water.
  Saline may be used for irrigation, but should be
  avoided as the primary wetting agent.
• Apply either side of dressing in direct contact
  with wound bed and walls, and overlap wound edges
  onto healthy skin.
• Cover Silverlon NPD with negative pressure foam
  or fill media ( if using Versatile 1) and drape
  per manufacturers instructions.
• Change Silverlon NPD when you change foam or
  fill media.
• Silverlon NPD may be used for up to 7 days.

10
Silverlon Negative Pressure Dressings

• Frequently Asked Questions
• Can these dressings handle highly exudative
  wounds ?
• The unique dual flow ports allow for rapid
  fluid passage into the media, making it an ideal
  dressing over highly exudative wounds, with or
  without the use of NPWT.
• Can these dressings be rinsed and reused ?
• Based on professional discretion, all these
  dressings may be rinsed and reused, provided they
  are substantially free of debris and exudate.
• Can these dressings also be used without negative
  pressure therapy ?
• Absolutely, simply follow Silverlon wound
  contact protocol.
• See dressing package for Indications and Caution.

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Five Clinical CasesCombining Negative Pressure
Therapy with Silverlon Negative Pressure
Dressings, and Bilayered Living Skin Equivalent
12
Case Study 1

• 82 y/o woman with diabetes, peripheral vascular
  disease, and neuropathy
• Ulcer developed from thermal injury (electric
  blanket). Failed to respond to conventional
  treatment.

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Case Study 1 (Continued)
1/12/02 Necrotic Diabetic Heel Ulcer 5.1 x 7.0cm
1/12/02 s/p debridement, pre-Apligraft,
Silverlon, KCI Wound Vac
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Case Study 1 (Continued)85 Wound Volume
Reduction in 90 days
1/14/02 2 days s/p Apligraft, Silverlon, Wound
Vac
4/10/02 2 days s/p 2nd apligraft, Silverlon,
Wound Vac 2.1 x 2.0cm
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Case Study 2Rapid Healing in 90 days
12/31/01 Healed at 3 months
10/3/01 Admit 4.7 x 6.0 x 1.8cm
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Case Study 3Rapid Healing In 30 Days
12/10/01 s/p Silverlon, Vac, Apligraft 0.6 x
1.0 cm
11/12/01 Silverlon Wound Vac 4.0 x 4.7 x 0.7
cm
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Case Study 4

• 73 y/o woman with chronic steroid dependent
  asthma, hypertension bilateral venous stasis
  disease and hx of phlebitis.
• 3 month old painful leg wound that originated
  from an insect bite and has failed conventional
  therapy

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Case Study 4 (Continued)
Admit s/p debridement s/p 12 of
Wound Vac
6/11/01 application of Apligraf continue Vac
and Silverlon reduced pain
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Case Study 4 (Continued)
7/2/01 s/p Apligraf Vac Continue
Silverlon and Dynaflex
8/28/01 Healed in less than 3 months
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Case Study 5

• 63 y/o woman with chronic steroid dependent
  rheumatoid arthritis, Sjogren Syndrome,
  osteoporosis and iron deficiency anemia present
  with a a traumatic painful leg Ulcer.

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Case Study 5 (Continued)
11/26/01 Admit 9.9 x 8.5cm
11/29/01 s/p debridement application Apligraf
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Case Study 5 (Continued)
12/03/01 1st dressing change, reduced pain, went
on to rapid healing
11/29/01 Apligraf, Silverlon, Vac
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COMPARATIVE STUDY OF COMBINATION
THERAPYSILVERLONNPD with VAC VS. VAC ALONE

• Non-Healing Chronic Wounds Associated With Tissue
  Defects of the Legs and Feet,
• Stanley N. Carson, M.D. Fountain Valley Regional
  Hospital. Presented at SAWC, 2005
• Efficacy and Cost Savings Analysis at 90 days of
  Treatment.
• Patient Population VAC Alone N40
  Silverlon NPD VAC N40
• Age 16 90 years
  15 89 years
• Male
  21 21
• Female
  19 19
• Diabetes
  18 18
• Tobacco Use 7
  7
• Renal Failure 5
  5
• Ischemia ABI 0.5-0.8 12
  12
• Wound Areas Avg. 10cc
  Avg. 12cc

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COMPARATIVE STUDY OF COMBINATION
THERAPYSILVERLONNPD with VAC VS. VAC ALONE
(Continued)

• RESULTS VAC Alone
  Silverlon NPD VAC
  
• Percent healed at 90 days 50
  87.5
• Infection
  15 0
• No. of kits/patient 30
  18
• Nurse time/ patient 17.5
  hrs. 10.5 hrs.
• Savings per patient
• w/ Silverlon NPD -
  3,073.50
• __________________________________________________
  ________________
• Protocol
• VAC alone VAC dressings changed
  every 3 days.
• Silverlon VAC VAC dressings changed
  every 5 days.

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One Year Value Analysis Projection Using
Silverlon withNegative Pressure Wound Therapy

• Expected Annual Cost Savings Analysis Using
  Medicare Reimbursement Pricing
• 2003 actual utilization at 800 bed teaching
  hospital with an average of 18 active VACs
• Silverlon Negative Pressure Dressing with VAC
  vs. VAC with Standard Kit

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One Year Value Analysis Projection Negative
Pressure Wound Therapy (Continued)

• VAC Alone --- Standard KCI Protocol
• 3 Dressing Changes Per Week
• Costs
  
  
• Actual NPT Patient Days - 2003
  6,570
• Actual Rental Charge (Per Day Per Machine)
  70.00 459,900
• Actual Kit Usage - 3 kits/wk/patient (total
  units) 2,190
• Avg.Kit Cost (foam/drape) avg. of all sizes
  28.00
  61,320
• Avg. Nursing Time Per Kit Change - 38 min.
  each 1,387hrs. _at_ 27/hr 37,449
• Avg. Infection Rate NPT Related
  12
• 
  Total 558,669
• VAC Combined with Silverlon NPD --- Silverlon
  Protocol
• 1 Dressing Change Per Week
• Costs
• Est. NPT Patient Days with Silverlon - 2003
  5,256
• Est. NPT Rental Charge (Per Day Per Machine)
  70.00 367,920
• Est. Kit Usage 1 kit/wk/patient (total
  units) 938
• Avg. Kit Cost 28.00
  26,264

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One Year Value Analysis Projection Negative
Pressure Wound Therapy (Continued)

• Expected Annual Savings
• Rental Savings from fewer rental days needed
• 459,900 - 367,920 91,980 or 20
• Disposable Kit Savings from fewer kits used
• 2,190 938 1,254 saved 35,056 or 57
• Nursing Time Savings from fewer kit changes
• 1,254 kits _at_ 38 minutes 793 hrs. or 57
• Payroll Dollars Saved (793 nurse hours x 27
  avg.) 21,411
• Overall Expected Annual Savings 143,074 or
  25
• Can your silver dressing do this ?

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Savings Calculator Hospital(file on this CD as
NPD Savings Calculator Hospital.xls)
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Savings Calculator Home Health( file on this
CD as NPD Savings Calculator Home Health.xls)
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SilverlonContact Information
Argentum Medical, LLC. (Customer Service)
1-888-551-0188 More information is available at
SILVERLON.COM Silverlon Outlasts, Outperforms,
Outnumbers