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Tuberculosis in the United States

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... defined as resistance to at least isoniazid and ... plus resistance to any fluoroquinolone and at least one of three injectable second-line anti-TB drugs. ... – PowerPoint PPT presentation

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Title: Tuberculosis in the United States


1
Tuberculosis in the United States
National Tuberculosis Surveillance System
Highlights from 2007
Division of Tuberculosis Elimination Centers for
Disease Control and Prevention
2
Reported TB Cases United States, 19822007
No. of Cases
Year
Updated as of April 23, 2008.
3
TB MorbidityUnited States, 20022007
Year No. Rate
  • 2002 15,056 5.2
  • 2003 14,837 5.1
  • 2004 14,501 4.9
  • 2005 14,065 4.7
  • 13,754 4.6
  • 13,299 4.4

Cases per 100,000, updated as of April 23,
2008.
4
TB Case Rates, United States, 2007
D.C.
lt 3.5 (year 2000 target)
3.64.4
gt 4.4 (national average)
Cases per 100,000.
5
TB Case Rates by Age Group United States,
19932007
Cases per 100,000
Age Group (years)
Updated as of April 23, 2008.
6
Reported TB Cases by Age Group, United States,
2007
lt15 yrs (6)
gt65 yrs (19)
1524 yrs (12)
2544 yrs (32)
4564 yrs (30)
7
TB Case Rates by Age Group and Sex, United
States, 2007
Cases per 100,000


8
TB Case Rates by Race/Ethnicity United States,
19932007
Cases per 100,000
All races are non-Hispanic. In 2003,
Asian/Pacific Islander category includes persons
who reported race as Asian only and/or Native
Hawaiian or Other Pacific Islander
only.Updated as of April 23, 2008.
9
TB Case Rates by Age Group and Race/Ethnicity,
United States, 2007
Cases per 100,000
Age Group (yrs)
All races are non-Hispanic. Persons reporting
two or more races accounted for less than 1 of
all cases.
10
Reported TB Cases by Race/Ethnicity United
States, 2007
American Indian or Alaska Native (1)
White (17)
Asian (26)
Native Hawaiian or Other Pacific Islander (lt1)
Hispanic or Latino (29)
Black or African-American (26)
All races are non-Hispanic. Persons reporting
two or more races accounted for less than 1 of
all cases.
11
Number of TB Cases inU.S.-born vs. Foreign-born
Persons United States, 19932007
No. of Cases
Updated as of April 23, 2008.
12
Trends in TB Cases in Foreign-born Persons,
United States, 19872007
No. of Cases
Percentage
Updated as of April 23, 2008.
13
Reported TB Cases by Origin and Race/Ethnicity,
United States, 2007
U.S.-born
Foreign-born
American Indian or Alaska Native (3)
White (5)
Asian (2)
Hispanic or Latino (38)
White (33)
Asian (43)
Black or African American (45)
Native Hawaiian/Other Pacific Islander (lt1)
Hispanic or Latino (17)
Black or African American (13)
All races are non-Hispanic. Persons reporting
two or more races accounted for less than 1 of
all cases. American Indian or Alaska Native and
Native Hawaiian or Other Pacific Islander
accounted for less than 1 of foreign-born cases
and are not shown.
14
Percentage of TB Cases Among Foreign-born
Persons, United States
1997
2007
DC
gt50
2549
lt25
Updated as of April 23, 2008.
15
TB Case Rates in U.S.-born vs. Foreign-born
Persons United States, 19932007
Cases per 100,000
Updated as of April 23, 2008.
16
TB Case Rates in U.S.-born vs. Foreign-born
Persons United States, 19932007
Cases per 100,000
Includes the same data as slide 15, but rates
presented on a logarithmic scale. Updated as of
April 23, 2008.
17
Countries of Birth of Foreign-born Persons
Reported with TB United States, 2007
Mexico (24)
Other Countries (39)
Philippines (12)
Rep. Korea (3)
Viet Nam (7)
Haiti (2)
India (8)
China (5)
18
Percent of Foreign-born with TB by Time of
Residence in U.S. Prior to Diagnosis, 2007
Foreign-born TB patients for whom information
on length of residence in the U.S. prior to
diagnosis is unknown or missing.
19
Primary Anti-TB Drug Resistance United States,
19932007
Resistant
Updated as of April 23, 2008. Note Based on
initial isolates from persons with no prior
history of TB. Multidrug resistant TB (MDR TB) is
defined as resistance to at least isoniazid and
rifampin.
20
Primary MDR TBUnited States, 19932007
No. of Cases
Percentage
Updated as of April 23, 2008. Note Based on
initial isolates from persons with no prior
history of TB. MDR TB defined as resistance to
at least isoniazid and rifampin.
21
Primary Isoniazid Resistance in U.S.-born vs.
Foreign-born Persons United States, 19932007
Resistant
Updated as of April 23, 2008. Note Based on
initial isolates from persons with no prior
history of TB.
22
Primary MDR TB inU.S.-born vs. Foreign-born
Persons, United States, 19932007
Resistant
Updated as of April 23, 2008. Note Based on
initial isolates from persons with no prior
history of TB. MDR TB defined as resistance to at
least isoniazid and rifampin.
23
XDR TB Case Count defined on Initial DST by
Year, 19932007
Case Count
Year of Diagnosis
Drug susceptibility test. Reported incident
cases as of April 23, 2008. Extensively
drug-resistant TB (XDR TB) is defined as
resistance to isoniazid and rifampin, plus
resistance to any fluoroquinolone and at least
one of three injectable second-line anti-TB
drugs.
24
Reporting of HIV Test Results in Persons with TB
by Age GroupUnited States, 19932006
with Test Results
2006
Updated as of April 23, 2008. Note Includes
TB patients with positive, negative, or
indeterminate HIV test results. Persons from
California reported with AIDS only through 2004.
(HIV test results are not reported from
California)
25
Estimated HIV Coinfection in Persons Reported
with TB, United States,19932006
Coinfection
2006
Updated as of April 23, 2008. Note Minimum
estimates based on reported HIV-positive status
among all TB cases in the age group.
26
Mode of Treatment Administration in Persons
Reported with TB United States, 19932005
Updated as of April 23, 2008. Directly
observed therapy (DOT) Self-administered therapy
(SA)
27
Completion of TB Therapy United States,
19932005

Percentage
Updated as of April 23, 2008. Healthy People
2010 target 90 completed in 1 yr or less. Note
Persons with initial isolate resistant to
rifampin and children under 15 years old with
meningeal, bone or joint, or miliary disease
excluded.
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