IMMUNOMODULATORS FROM NATURAL SOURCES

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IMMUNOMODULATORS FROM NATURAL SOURCES Maroti M
Jeurkar Pharmacognocy Department, Hi-tech
college of pharmacy, chandrapur.
Abstract- Herbal immunomodulator is a substance
which stimulates or suppresses the immune system
including both innate and adaptive immune
responses. The modulation of immune system by
various medicinal plant products has become
subject for scientific investigations currently
worldwide. A number of Indian medicinal plants
and various Rasayanas has been possessing
immunomodulatory activity. Some of these natural
immunomodulators from various plant sources such
as Tinospora cordifolia, Asparagus racemosus,
Withania somnifera, Azadirachta indica and
Emblica officinalis can be used to influence the
immune system. Keywords immunomodulator, Indian
medicinal plants, herbal medicinal plant  
Immunomodulators from natural sources
Introduction Various Natural compounds have
contributed enormously to immunomodulatory
therapeutics. There are thousands of natural
compounds that are known to influence the immune
system by either affecting the functions of
immune cells. The Administration of the powdered
medicinal plants as Rasayanas has been possessing
immunomodulatory activity from various Indian
medicinal plants and herbal medicinal plant. In
recent years, there is a tremendous interest in
the possible role of nutrition in prevention of
corona disease. In this context, immunological
agent especially derived from natural sources
that can modify the immune response, either by
enhancing or suppressing the immune system. They
are also used to fight infections, prevent and
treat certain diseases.8 Indian medicinal plants
provide a rich source of immunity. The medicinal
plants that show significant immunomodulatory
activity are as follows. Objective To evaluate
and study the immunomodulatory activities of some
natural plants.  
Sr.no Herbal Plant Species Active Compounds Therapeutic Uses
1 Gudvel (Tinospora cordifolia) Berberine, Tinocordiside Magnoflorine, antiviral, Anticancer immunomodulator,
2 Neem (Azadirachta indica) nimbn, nimbinin, nimbidin Antiviral,immunity developer,antiseptic,
3 Amla (Emblica officinalis) Vitamin C, tannins, alkaloid Analgesic, Antitussive, immunomodulator
4 Aswagandha (Withania somnifera) Withania immunomodulator, anti-inflammatory
5 Shatavari (Asparagus racemosus) shatavarins Immunomodulator,
References-1.C Barathi,et al., IJOCRISSN NO
2279-543X Volume 7, Issue 12, 2018 Page No
585 2..Asha Roshan et al, ,Journal of
Phytomedicine 0101 2015 3..K.H. Khan,. Intl., 2
(4) 218-228, 2009 4..Leemon devis, et al
,JOE,volume 71, isshu 1-2,, July 2000, Pg
193-200 5..Manish Gautam .et al., Journal of
Ethnopharmacology 121 (2009) 241247
Conclusion- As per the study, it will concluded
that this natural herbal plants produce the
immunodilator activity and all of that herbal
medicinal plant are easily available so used that
immunodilator plants for develop the immunity
response.