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What is infertility? How does it influence a
couple's life?

• Infertility refers to an incapability to conceive
  after 12 months of regular unguarded lovemaking
  sessions.
• Infertility is the biological failure of a person
  to take part in conception, or to a female who
  fails to carry out a pregnancy to full term.
• The costs of infertility are manifold and can
  include societal consequences and personal
  suffering.
• The suffering of infertility has innocently led
  to a disrespect for the emotional responses that
  couples experience including sorrow, loss of
  control, stigmatization, and a disturbance in
  their normal life.
• Barrenness bears a stigma that may cause
  considerable anxiety and disappointment in
  couples who fail to conceive.

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What are the underlying factors responsible for
infertility?

• There are several underlying factors responsible
  for causing infertility including sensually
  transmitted infections, certain inherited
  factors, diabetes mellitus, thyroid disorders,
  undiagnosed or untreated coeliac disease, adrenal
  gland ailment, hypopituitarism, damage of DNA,
  etc.
• Certain environmental factors or lifestyle
  factors are also responsible for causing
  infertility such as smoking and toxins like
  organic solvents, silicones, physical or chemical
  agents, and pesticides.

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How does HCG Pregnyl Injections act to treat
infertility?

• Pregnyl 5000 iu comprises of a generic hormone
  called Human Chorionic Gonadotropin (HCG). It
  causes the growth and discharge of an egg from
  the female ovary.
• It also helps in the formation of androgens in
  men and this causes the development of secondary
  sex characteristics, which maintain the
  testicular descent.
• Pregnyl 10000 iu HCG Injections helps in the
  formation of testosterone in the Leydig cells
  that cause the creation of sperm in the
  seminiferous tubules.

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What is the dosing regimen of Pregnyl injection?

• Pregnyl injection is commercially accessible in
  three different dosing strengths of 2000IU,
  5000IU, and 10,000IU.
• Dose for the management of ovulation trouble in
  women A woman should inject 5000-10,000IU of
  Pregnyl via the subcutaneous (SC) or
  intramuscular (IM) route followed by the last
  dose Menotropins.
• Dose for the treatment of Hypogonadotrophic
  hypogonadism in male A man should inject 4000IU
  of HUCOG via the SC or IM thrice a week for 6 to
  9 months, followed by 2000IU of Pregnyl thrice a
  week for an additional 3 months.
• Dose for the treatment of pubertal
  Cryptorchidism A dose of 5000IU of Pregnyl
  should be injected via the SC or IM on every
  other day for four injections.

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What are the undesired effects of Pregnyl
injection?

• Although, Pregnyl injection is a safe treatment
  of infertility, but sometimes its use may cause
  some undesired effects such as
• headache
• fatigue
• edema
• gynecomastia,
• agitation
• weariness
• bad mood
• pain or swelling at the site of injection

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Here, pay special attention while using HCG
Pregnyl 5000 iu 10000 iu

• Always try to use a sterile needle or syringe to
  inject Pregnyl injection.
• The use of Pregnyl injection may increase the
  risk of multiple pregnancies in women, so they
  should consult their physician before using this
  medicine.
• Do not recommend Pregnyl injection to children
  less than 4 years of age, as the safety and
  effectiveness of this medicine in these children
  have not been confirmed.
• If you are pregnant women and a breastfeeding
  mother, then you must communicate your doctor
  before using Pregnyl injection.
• A woman before relying on the treatment of
  Pregnyl injection must follow with a
  gynecological exam.

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• Beside these common factors, there are other
  factors responsible for causing fertility
  troubles in women including ovulation troubles,
  pelvic inflammatory disease, uterine trouble,
  endometriosis, age-related factors, tubal
  blockage, and advanced maternal age.

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