Systemic Lupus Erythematosus Market - Growing Opportunities

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Frontier Pharma Systemic Lupus Erythematosus
Identifying and Commercializing First-in-Class
InnovationbyGBI Research

• Explore all reports for  Autoimmune Drugs
  market
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Frontier Pharma Systemic Lupus Erythematosus
Identifying and Commercializing First-in-Class
Innovation

• The Systemic Lupus Erythematosus (SLE) drug
  market is currently under-served by non-generic,
  targeted therapies. Whilst the only Food and Drug
  Administration (FDA)-approved biologic, Benlysta
  (belimumab), generated sales of 111m in 2012,
  there is little evidence that the drugs
  performance is significantly superior to other
  B-cell targeted therapies such as Rituxan
  (rituximab), which is often used off-license to
  treat refractory SLE patients. Therapeutics
  entering the market therefore do not face the
  staggering level of competition from currently
  marketed programs as in other markets such as the
  Rheumatoid Arthritis (RA) market. Emerging market
  entrants that appear to offer significant
  therapeutic benefits are likely to cause dramatic
  changes to the market landscape.
• A growing understanding of the signaling pathways
  underlying SLE pathophysiology including, but not
  limited to, B cells, T cells and intracellular
  kinases, is translating into a higher number of
  novel, and more importantly, first-in-class
  targeted therapeutics entering the developmental
  pipeline. In particular, a high level of
  investment in the development of
  cytokine-blocking strategies is evident, as
  therapies targeting the interferon pathway are
  relatively common in the pipeline.
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Frontier Pharma Systemic Lupus Erythematosus
Identifying and Commercializing First-in-Class
Innovation

• Scope
• The report analyzes the market for SLE
  therapeutics and the pipeline products in that
  market, with particular emphasis on
  first-in-class programs.
• A brief introduction to SLE, including symptoms,
  pathophysiology, disease scoring indices and
  overview of pharmacotherapy
• In-depth analysis and literature review on
  marketed products, including analyses of their
  safety, efficacy, treatment patterns and
  strengths/weaknesses, based on published clinical
  trials, as well as a reference table of drugs in
  terms of safety and efficacy
• Overview of how innovation products are
  contributing to the market for SLE therapeutics
• Comprehensive review of the pipeline for
  first-in-class therapies, which is analyzed on
  the basis of phase distribution, molecule types
  and molecular targets, as well as administration
  routes
• The changing molecular target landscape between
  market and pipeline, and, in particular, focal
  points of innovation
• First-in-class molecular targets, highlighting
  early-stage programs for which clinical utility
  has yet to be evaluated, as well as an in-depth
  literature review on novel molecular targets
• Complete Report Available _at_
• http//www.rnrmarketresearch.com/frontier-pharma-s
  ystemic-lupus-erythematosus-identifying-and-commer
  cializing-first-in-class-innovation-market-report.
  html .

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Frontier Pharma Systemic Lupus Erythematosus
Identifying and Commercializing First-in-Class
Innovation

• Reasons to buy
• The report will assist the business development
  strategies of companies that wish to develop
  novel therapies with improved benefits to
  existing treatments. It will also be of interest
  to companies seeking to expand their pipeline
  portfolio through licensing agreements and
  co-development deals. Primarily, the report will
  allow clients to identify and understand market
  opportunities and the emerging competitive
  environment. It will also allow you to -
• Understand the SLE pipeline and the factors which
  indicate that it is becoming more innovative
• Understand the overall focal shifts in
  therapeutic molecular targets for the treatment
  of SLE
• Understand the distribution of the pipeline
  programs by phase of development, molecule type
  and molecular target
• Identify the list of first-in-class programs that
  are potentially open to deal-making opportunities
• Understand the first-in-class developmental
  programs and gauge the current clinical
  effectiveness based on animal models
• Buy a copy of report _at_
• http//www.rnrmarketresearch.com/contacts/purchase
  ?rname145685 .

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Frontier Pharma Systemic Lupus Erythematosus
Identifying and Commercializing First-in-Class
Innovation

• Table of Contents
• 1 Table of Contents 41.1 List of Tables 51.2
  List of Figures 6
• 2 Introduction 72.1 The Case for Innovation in
  Systemic Lupus Erythematosus 72.2 Growing
  Opportunities for Biologic Products 72.3
  Diversification of Molecular Targets 72.4
  Innovative First-in-Class Product Developments
  Remain Attractive 82.5 Changes in the Clinical
  and Commercial Environment to be More Favorable
  to Products Targeting Niche Patient Populations
  and Indications 82.6 Sustained Innovation 8
• 3 Systemic Lupus Erythematosus 93.1 Disease
  Overview 93.2 Epidemiology 9
• Request Sample copy of this report _at_
  http//www.rnrmarketresearch.com/contacts/request-
  sample?rname145685 .

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Frontier Pharma Systemic Lupus Erythematosus
Identifying and Commercializing First-in-Class
Innovation

• For more details contact Mr. Priyank Tiwari
  sales_at_rnrmarketresearch.com / 18883915441

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