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If you find an issue with the presentation output, click here. We'll get back to you within the next 48 hours. HEPAGEN - Metabolic Management of Cow Health

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2-methyl-2-phenoxy-propionic acid (HepagenTM - Fatro) is the only PPAR-alpha activator available in veterinary medicine. 2-methyl-2-phenoxy-propionic acid by binding to PPAR-alpha up-regulates the transcription of several genes involved in lipid and glucose metabolism. As a result it promotes the activation of mitochondrial and peroxisomal beta-oxidation pathways and liver gluconeogenesis. Enhanced lipid oxidation brings to the reduction of triglyceride accumulation in hepatocytes, recovery of liver functions and increased energy availability for glucose production. Direct up-regulation of genes involved in gluconeogenesis intensifies hepatic glucose output and restores energy balance. The anti-inflammatory properties of this PPAR agonist further help cows, considering that inflammatory conditions play a role in the pathogenesis of fatty liver and many other diseases. – PowerPoint PPT presentation

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