SIBERIAN CHAGA

1
SIBERIAN CHAGA

• Pacifex Investment Ltd
• for
• Natural Products Expo Asia 2003

2
MEDICINAL MUSHROOMS Healing Abilities of an
Ancient Remedy

• For thousands of years, revered throughout world
  esp. China and Japan as folk medicine
• Documented in Shen Nong Ben Cao Jing in 100 B.C.
  as the King of the Herbs. In Russian folklore,
  Chaga used since the 16th Century
• For past 40 years, modern scientific studies
  demonstrate proven pharmacological effects for
  the immune, hormonal and central nervous system.
  A few drugs developed ie. specifically beta
  glucans for cancer and immunity system

3
MEDICINAL MUSHROOMS Considered the Third Kingdom

• Neither plant or animal yet its DNA make-up (30)
  is closer to humans than plants
• Valued throughout Asia and Europe as both a
  health food and as a medicine
• According to TCM, medicinal mushrooms improve
  health, preserve youth and increase longevity and
  boost Chi, or life energy
• But the biochemistry of these mushrooms are
  complex and far from being thoroughly studied.
  About 200 species with anti tumor and anti
  immunity properties, the most famous being
  Ganoderma Lucidum, known as Lingzhi in China or
  Reishi in Japan

4
MED MUSHROOMS King of the Herbs

• Estimated 140,000 types of mushrooms and fungi,
  ie penicillin mold is one
• 38,000 are mushroom species including 200 of
  demonstrated medicinal value
• 75 species being in China
• But just a few defined as truly Superior
• Scientifically coined as
• edible higher Basidiomycetes mushrooms
• The greatest success of the pharma industry in
  the 20th century antibiotics came from molds,
  closely related yet surprisingly med mushrooms
  are used mainly as supplements

5
BASIDIOMYCETES MUSHROOMS(approx 200 types with
medicinal value)

• MOST COMMON SPECIES
• Inonotus Obliquus (Siberian Chaga)
• Agaricus blazei Murill
• Ganoderma lucidum
• (Lingzhi / Reishi)
• Lentinus edodes
• Cordyceps sinensis
• Grifola frondosa
• Hericium erinaceus
• Cor. Versicolor (Yunzhi)
• Tremella fuciformis
• Phellinus linteus
• Hericium erinaceus

• SMORGASBORD MED VALUE
• Immunity enhancer
• Anti cancer/anti tumor
• Anti viral/bacterial
• Lowers cholesterol
• Liver, kidney, lungs
• Cardiovascular
• Blood sugar/diabetes
• Chemotherapy adjunct
• Stomach/gastric system
• Candida albicans
• Hepatitis and HIV
• Nerve tonic/stress
• Melanoma / skin care

6
MODERN SCIENTIFIC STUDIES

• Over 1600 Research Studies
• In vivo in vitro studies over past 40 years,
  incl cancer research, immune deficiencies
  diabetes HIV hormonal imbalances
• Over 40 Cancer drugs extracted such as AHCC,
  Lentinan (shiitake) PSK (Yunzhi), Schizophyllan,
  D-fraction, Reishi (mannentake), Betulin
  (Siberian Chaga) and others

• Siber Chaga Studies Include
• Cancer research breast, lung, stomach,melanoma
• Pulmonary, diabetes,
• rectum, ulcers, TB, liver
• cardiovascular-related
• Leukemia, SOD, HIV
• Supportive clinical result
• 85 and 78 reduction on lung and breast
  carcinoma, respectively
• 89.9 erythrocytes in bone marrow

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THE MAGIC OF MUSHROOMS

• Agaricus blazei murill Founded in Brasil to
  protect immune system. Popular in Japan for
  cancer, lower cholesterol blood pressure
• Reishi (Ganoderma lucidum) Called Lingzhi
  widely researched. For immune, cardiovascular.
  200 Ganoderma species
• Maitake (Grifola frondosa) Indigenous to Japan.
  D-fraction approved for clinical phases in 1998
  by FDA

• Shiitake (Lentinus edodes) extracts approved
  1985 by FDA in Japan for anti cancer.
• Cordyceps sinensis Found 12000 ft above sea
  level in China Nepal. For stamina, endurance
  and sex drive.
• Tremella fuciformis More than 70 dietary fiber
  for skin weight control.
• Coriolus versicolor Known as kawaratake or
  Yunzhi. PSK approved for cancer in Japan China

8
HOW CAN A SINGLE PRODUCT HAVE SO MANY HEALTH
BENEFITS?

• Assess the Nutritional Value of Medicinal
  Mushrooms, in particular Siberian Chaga
• Evaluate the Active chemical compounds and how
  they affect the immune, hormonal and central
  nervous system
• Cite Siberian Chaga case study examples
• Just as there are many medicinal mushrooms to
  contribute to immunity protection, which one is
  best for me is a question frequently asked

9
NUTRITIONAL VALUE OF MEDICINAL MUSHROOMS APPEAR
SIMILAR

• Generally rich in minerals such as Vitamin B1, B2
  and B3 and many Amino Acids. Contains Ergosterol
  (Vitamin D2) which is not found in vegetables.
  High in dietary fibers, low calories
• Medicinal mushrooms contain a complex cocktail
  of immune-activating compounds
• Beta glucans are the COMMON compounds considered
  complex carbohydrates or polysaccharides. Also in
  algae, yeast, oats
• Immunity effectiveness inter-linked to
  protein/amino acid complexes and heteroglucans,
  sterols, triterpenes, SOD, Saponins and other
  trace minerals

10
CHEMICAL / NUTRITIONAL VALUES DIFFICULT TO
DIFFERENTIATE

• Based on records of Assays (per 100 grams)
• Components Sib Chaga Agaricus Linghzi
• Protein g 2.3 43 8-12
• Diet Fiber g 58.2 6.1 17-20
• Fat/Lipid g 1.7 3.9 1.9
• Cellulose
• .. Saccharide g 19.3 lt41.5 54-56
• Beta Glucan g lt13 9.3 1.2-6.2
• Vitamins (mg)
• .. Ergosterol, Thiamin (B1) Riboflavin (B2)
  Niacin (B3)
• Trace Minerals Ca K P Zn Cu Mg Cl Mn Se Si Fe Na
• Sterols, Triterpenes, Amino Acids Glycosides SOD
  (anti oxid
• Sib Chaga contains 215 phytonutrients Lingzhi
  180 or so

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MED MUSHROOMS ARE IMMUNITY STIMULATORS
ADAPTOGENS

• Modern scientific research demonstrate that beta
  glucans are largely responsible for warding off
  tumors, cardiovascular, immune deficiencies,
  hormonal imbalances, viral, bacterial and
  parasitic diseases
• Several beta glucans extracted for cancer therapy
• Medicinal mushrooms are biologically described as
  adaptogens, or as natural-plant derived agents
  that
• Cause no harm on the body
• Stimulate the nervous, hormonal immune system
• Exert non specific regulatory functions i.e.
  blood pressure, blood sugar, cholesterol,
  respiratory, hormonal glands, inflammatory
  joints, etc
• In ancient TCM, Med. Mushrooms considered the
  elixir of life providing equilibrium or Yin/Yang

12
HOW BETA GLUCANS FUNCTION

• Beta Glucans and complex proteins do not attack
  virus, bacteria, cancer cells directly.
• Instead sets off alarm to activate different
  immune systems to bring out defensive weapons.
• Such as macrophage cells including T cells, B
  cells, natural killer cells. Then activating
  antibodies custom formulated to fight specific
  invaders.

• CLINICAL TRIALS PROVE
• Prevention of oncogenesis
• Direct anti tumor activity
• Synergy with chemotherapy
• Prevents tumor metastasis
• Host of Beta Glucans
• Over 17 in Agaricus blazei
• 29 in Inonotus Obliquus
• 57 in Grifola frondosa
• 45 in Ganoderma tsugae
• 15 in Hericium erinaceus

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MOST POWERFUL INGREDIENTBeta-1, 3-D GLUCAN

• Mushroom cell walls contain a multiple number of
  beta glucans that are interlinked to proteins,
  amino acids, anti oxidants etc. Siberian Chaga
  has 29 beta factions
• Alpha Beta Glucans are complex carbohydrates or
  commonly known as polysaccharides. Their
  structural interaction, molecular weight and
  effects on cellular immunity makes them
  difficult to isolate, research and apply under
  the modern medicine philosophy of One disease,
  one chemical compound
• However all effective med mushrooms MUST HAVE the
  1,3-D beta glucan structure for proper immune
  function. Different mushrooms have different
  molecular weights, water solubility and ability
  to permeate the stomach walls after oral
  ingestion.

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SIBERIAN CHAGA

• Used as folk medicine since 16th Century in
  Russia and East Europe
• Modern research confirm efficacy as anti-tumor
  anti-viral, anti-parasitic

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CHAGA FACT SHEET

• Woody fungus, with black deeply scarred outer
  surface resembling burnt charcoal brown inner
  layer
• Cell membrane walls very very hard, similar to
  spores of Lingzhi variety.
• Naturally grown in Siberia. Best quality from
  black birch trees. White birch trees prevalent in
  Hokkaido, N Canada, Finland
• Approved by Russian Medical Research Council and
  Ministry of Health, Labour and Welfare in Japan
  and Korea. Classified under WTO Tariff Code as
  medicinal mushroom fungi

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MANY VARIETIES OF S. CHAGA

• Over 10,000 fuscoporia obliqua, but only 2-3
  species demonstrate strong anti viral, anti
  bacteria anti parasitic effects
• The birch tree withers dies within 2-3 months
  after Chaga harvest, Natures tell tale way to
  identify the best grades. Siberian species grow
  best in wintry conditions below minus 40 deg C at
  least 4-5 months per year
• Birch tree grows in 13 years and another 7 years
  for Chaga sap to grow on its trunk
• Latin Name Inonotus Obliquus, others I.
  Radiatus, I. Sciurinus, I.Tabacinus, I.Orientolis

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SIB CHAGA GROWS BEST (-40 C)
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SIBERIAN CHAGA FOLK REMEDY

• Used in folk medicine since 16th century in
  Russia East Europe for gastritis, ulcers, TB of
  bone, cancer, asthma, bronchitis, digestive
  system, skin eczemas, blood pressure
• Drunk as a hot tea concoction
• Chaga also burned and the smoke breathed in for
  lung and pneumonia disorders.
• Also combined with tobacco and smoked
• Small pieces placed over skin (like Moxa) and
  slowly burnt, for skin irritants, arthritis, skin
  infections

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SIBERIAN CHAGA INGREDIENTS

• Contains 215 phytonutrients including 29
  polysaccharide or beta glucan derivatives
• Includes heteroglucans, triterpenes, sterols,
  anti oxidants, saponins, amino acids, trace
  minerals, vitamins, dietary fibers combining
  together in complex integrated compounds to
  enhance the immune and hormonal system.
• Siberian Chaga, unlike the other medicinal
  mushrooms contain an exceptional amount of
  Betulinic acid and SOD (anti oxidant) content

20
BETULINIC ACID

• Betulinic acid is a pentacyclic triterpene
  available from several botanical sources,
  including the bark of birch trees
• Betulinic acid has been tested for Melanoma
  cancer, retards HIV infections and for eczema and
  other skin conditions.
• In Russia East Europe North America, birch bark
  is used in teas to treat stomach and intestinal
  problems such as diarrhea and dysentery

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CORRELATION OF BETA GLUCAN STRUCTURE AND ANTI
IMMUNITY

• Sib Chaga polysaccharides are comprised of
  different types of glycosidic linkages, ie (1,3)
  (1,6) beta glucans or (1,3) alpha glucans
• Each differs in configuration, anti immunity
  activity, molecular weight, size of branching
  chains and hence its complexity
• But research evidence indicate glucans work best
  in synergy with other protein-glucans, triterpene
  sterols and anti oxidants to enhance the bodys
  natural defense mechanisms to fight against
  different infectious conditions

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contin BETA GLUCAN IMMUNITY

• Beta-D Glucans trigger and stimulate many immune
  responses to fight against infections
• Activate microphage,T-helper, NK cells, B cells
• All of these increase the production of
  antibodies
• Beta glucans do not attack deficient/cancer cells
  directly however
• Macrophages are a kind of white blood cell that
  eat up pathogens such as bacteria, yeast cells,
  virus infected cells.
• Reside throughout the mucous membranes, ie
  digestive, urinary and respiratory tracts.
  Polysaccharides stimulate this protective shield

23
SOD (Super Oxide Dismutase)

• SOD is one of the most important anti oxidants in
  our body. SOD decreases as we age. Living well
  and exercising keep levels up. Chaga has far more
  SOD than Vitamins C,E and super foods like barley
  grass, seaweed prunes, fish oils, many
  aromatherapy essential oils.
• SOD are enzymes to keep our cell membranes supple
  and healthy. Research indicates its use for
  arthritis, side effects of cancer treatment,
  prostrate
• SOD uses in skin creams, burns, wounds,
  inflammatory
• SOD content in Sib Chaga is exceptional 35,000
  units/g
• Agaricus 1500
• Lingzhi 630
• Truffles 860
• Phellintus Linteus 1400
• (Source Dept of Health, Food Res Center, Japan)

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COMPARE SUPER FOODS (HI ORAC)(in units of Oxygen
Radical Absorbance Capacity)

• Food ORAC Scores
• Prunes 5770/100 ml
• Strawberry 1540
• Spinach 1260
• Oranges 750
• Carrots 210
• Essential Oils
• Cloves highest 10,000,000
• Oregano 153,007
• Eucalyptus 24,157
• Lavender 3669
• Daily Oxidant Levels 3000- 5000 ORAC or few
  servings of fruits and vegetables

• Siberian Chaga more Super
• 1 ml clove oil has anti oxidant power of 10 lbs
  carrots or 1 gal beet juice
• But 1 g Chaga has 4 times the anti oxidant power
  of the highest rated essential oils.
• Chaga is 20-25 times more potent than med
  mushrooms like Agaricus, Phellinus linteus,
  Truffles proven anti oxidants
• ORAC test Tufts University

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TRITERPENES AND PLANT STEROLS

• All the superior med mushrooms contain vast
  amounts of triterpenoids and sterols. Lingzhi has
  100 types including Ganoderenic Acid A and
  ergosterols and ergosterol peroxides
• Sib Chaga has a similar profile but far more
  Betulinic acid Lanosterol-linked triterpenes
• Lanosterols for anti bacteria, candidas,
  cholesterol
• Trametenolic acid for non insulin dependent
  diabetics
• Ergosterols for anti oxidant therapy and cancer
  drugs. Chaga 35.3 mg per gram versus
  Agaricus3.8 mg per gram (a ten fold difference)
• Inotodiol for influenza virus A B

26
continued

• Triterpenoids and sterols promote good blood
  circulation and assist to lower blood pressure
  and reduce cholesterol (LDL)
• Tests in Japan indicate increased red blood
  corpuscles flow 20 minutes after Chaga intake
• Sterol derivatives effective for prostrate,
  herpes, lupus, allergies, psoriasis as well
• High potency standardized extracts from Chagas
  Inotodiol compounds developed in Canada and
  Finland for influenza viruses

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SAPONINS FOR HEALTH

• First, it was fibers then anti oxidants, now it
  is saponins for health benefits. Saponins are
  glycosides mainly of triterpenoidal type
• Found in vegetables (spinach, tomatoes, alfalfa
  sprouts) oats as well in Siberian Chaga
• Research studies indicate lowers the risk of
  cancer, lowers cholesterol and long known as
  natural antibiotics for plants
• In addition birch trees contain other essential
  oils similar to wintergreen plants, methyl
  salicylate and high ORAC anti oxidant powers

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MODERN RESEARCH CONFIRM SIB CHAGA FOLK MEDICINE
REMEDIES

• Inotodiols extracted from Sib Chaga exhibit anti
  tumor properties, destroying over 100 Walker 256
  Carcinosarcoma cancer cells and MCF-7 human
  adenocarcinoma mammary cells.
• Lanosterols exhibit strong cytotoxicity towards
  carcinoma cells in vitro
• Triterpenes isolated and 100 effective against
  MCF-7 cells as well
• Ergosterol peroxide killed 100 of both cell
  lines.
• Tests indicate polysaccharides inhibit anti
  mutagenic effects by 80, Korea 2000

29
continued

• Polysaccharides of low and high molecular weight
  isolated and inhibited ratio against human lung
  carcinoma and breast carcinoma by 85 and 78
  respectively, 2001 Korea
• Induced erythrocytes in bone marrow in mice
  reduced by 88.9, 2002 Korea
• Inonotus extracts inhibited human cervical uteri
  tumor cells HeLa S3 in vitro, Poland
• Anti cancer on mouse leukemia P388 tumor in 1999,
  Japan
• Inhibit anti AIDS virus, 1994 Japan

30
continued

• Inhibit Melanin and prevent oncogenesis, Japan
  2002
• Reduced blood serum cholesterol, 2002 Japan
• Strong anti viral and anti oxidant effects,
  Kahlos 1994
• Inhibited HIV/AIDS virus, Japan 1996
• Strong anti HIV growth, Japan 1997
• Anti bacterial agent against pathogenic bacteria
  such as E-Coli, pneumobaccillus, pseudonones
  aeronginosa, Japan 1998
• Extracts for anti biotics, Japan 1996
• Anti inflammatory for skin care, Japan 1996

31
continued

• Anti virus clinical tests on dogs kidney,
  Hokkaido 1997
• Befungin drug approved by Russian Medical
  Academy, 1966
• Betulinic acid reduces cancer cells by 70 of
  type 293 cancer cells, Korea 1999
• Anti mutagenic effects on Salmonella typhimurium
  (TA 100), Japan 1996
• Effect of aqueous extracts from Inonotus Obliquus
  on mitotic and enzyme activities in human
  cervical uteri tumor cells, Poland 1997

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PATENTS FILED FOR S. CHAGA

• HIV extract and processing know-how, Japan 1998
• Anti mutagenic agent food, Japan 1997
• Processing know-how for HIV markers, Japan 1994
• Agent for suppressing HIV, Japan 1994
• AIDS virus culture of active ingredients, Japan
  1997
• Obtaining anti HIV agent, Japan 1997

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S. CHAGA KEY ADVANTAGES

• Many medicinal mushrooms are known for its immuno
  potentiating effects, but David Winston, a
  renowned herbalist claims Chaga is probably one
  of the strongest, if not the strongest we know
• Chaga has an advantage no other fungus has, that
  it contains Betulinic acid. Betulinic acid has
  demonstrated strong anti tumor activity with
  virtually no side effects and no toxicity
• Very cost effective compared to other edible
  Basidiomycetes mushrooms (between US 1.00 to
  2.00 per day), assuming one liter per day
  concoction drunk just like a herbal tea

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GANODERMA LUCIDUM

• Known as Lingzhi in Chinese or Reishi in Japan.
  Most widely researched Basidiomycetes mushroom
• Natural wild Lingzhi is very rare and very
  expensive. This specie contains the highest
  amount of Germanium of all mushrooms and approx
  45 polysaccharides (beta glucan fractions).
  Strong anti tumor and anti viral effect
• Techniques developed by Japan in the 1970s to
  grow artificial cultivated ganoderma lucidum, but
  thereafter inconsistent quality has become
  problematic
• Today, a proliferation of approx 200 species.
  Most are inexpensive with less than 1-year
  growing cycle with extreme variation in the of
  polysaccharide (beta glucan) content, leading to
  questionable expected results and a confused
  consumer market

35
MARKET SURVEY IN HK STORES(based on Ganoderma
Lucidum in pill form)

• Brand HK retail HK per gram polysaccharides
  
• A 250 34 9.2
• B 300 52 26.5
• C 380 99 10.3
• D 598 122 21.1
• E 460 214 3.6
• F 300 337 2.0
• G 480 1166 1.4
• H 198 2762 0.3
• It is no wonder consumers are confused since the
  labels do not specify the amount of active
  ingredients contained in the capsules (most are
  heavily diluted with fillers)

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AGARICUS BLAZEI MURILL (Himematsutake)

• Originating from highlands of Brasil, natural and
  wild Agaricus demonstrates strong anti immune
  properties. Studies in Japan in the 1980s and
  1990s confirm folk remedies.
• Very expensive since it is rare and effective.
  However similar to the Ganoderma Lucidum
  proliferation, techniques patented allowing
  growth of artificial cultivated Agaricus.
• As a result many ineffective species available to
  the consumer market. Not as effective as the wild
  and natural variations

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S. CHAGA DIRECTIONS FOR USE

• Add Chaga granulates to empty container (glass or
  porcelain is best). Add one liter of boiled water
• Soak for 12 to 24 hours allowing active
  ingredients to slowly extract into the liquid
  portion. Mixture turns to light brown tea color.
  DO NOT BOIL CHAGA HOWEVER
• Drink first cup 20 minutes before breakfast.
  Drink remaining liquid throughout the day. Chaga
  is NOT BITTER
• DO NOT throw away the residue grinds. Repeat
  process twice more by refilling boiled water and
  soak again for 12 or more hours. Hence 1 serving
  is very economical

38
DOSAGE AMOUNT PER LITER

• One teaspoon (approx 1 gram of Chaga granulates)
  is recommended for preventative treatment and
  wellness
• 2-3 teaspoons for disorders such as diabetes,
  ulcers, hepatitis, high cholesterol, pneumonia,
  skin treatment, blood sugars, cancer, HIV
• Drink a liter (4-5 cups) of this liquid
  concoction daily. The first visible effects are
  regular bowel movements and an improved skin
  complexion.
• Used chaga grinds can be added to family pet
  food, house plants or collected to wash ones
  face/bathe

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WHY AQUEOUS EXTRACTION?

• Medicinal mushrooms contain hundreds of
  phytonutrients, amino acids, beta glucans,
  sterols, lanosterols etc that slowly leach out
  after submersion. Some leach within minutes,
  others take days, others need to be boiled (ie
  Lingzhi spores)
• Chaga can be extracted 7 or more times under
  stringent vacuum and low temperature conditions.
  Each extraction leach out different
  proteins/heteroglucans because of its thick cell
  membrane walls. This technique is too difficult
  to do for home use (instead recommend to extract
  3 times with hot water)
• Pills or capsules are the modern worlds approach
  for the busy individual. However oral concoctions
  to reach the trillions of tissue cells are the
  best way to ingest

40
TESTS ON CELL PROLIFERATION

• Tests conducted in Korea on intestinal cells
  SNU-484 to determine the optimum dosage and
  extract amount required. Each test was conducted
  for 48 hours and the progressively higher dosages
  were evaluated. Data supports folklore dosages
  and aqueous extr technique
• Extract (mg/ml) Cell Number ( x 10'5 / dish)
• Control 19.5
• 1.5 9.2
• 3.0 8.9
• 6.0 7.4
• 12.0 3.3
• 18.0 1.9
• 24.0 0.0

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CHAGA HAS NO SIDE EFFECTS

• Siberian Chaga has demonstrated no side effects
  or nil toxicity effects.
• However for first time users, there is a strong
  probability of excessive bowel movements in the
  first 6 to 18 hours after the initial
  consumption. This symptom clears up the next day.
  Indicates body is detoxifying
• Furthermore, after excessive alcohol or shellfish
  intake, a majority of people notice similar
  cleansing effects.
• Chaga can used in conjunction with most
  pharmacology drugs and with chemo- or radiation
  therapy

42
CLINICAL STUDIES/OBSERVATIONS

• Female Age 38 Underwent radiation treatment for
  thyroid problem, feeling weak and nauseated for
  several months. Drank 1 g Chaga daily for 2
  months. Persistent pain around throat disappeared
  and energy level well up
• Male Age 58 Hepatitis with abnormal SGOT and
  SGPT count in lower 200-300 range. Also type 2
  diabetic. After 4 months of chaga daily, counts
  decreased to 45, still high but a dramatic
  improvement
• Female Age 50 Early menopause at age 49. After 4
  months of 1 g chaga daily, her menstrual cycle
  returned to normal. Skin complexion improved
  dramatically
• Female Age 39 Severe eczema on arms, legs and
  back. Cannot sleep at night. Tried several drugs,
  acupuncture and aromatherapy to no effect.
  Started drinking mega dose chaga and problem gone
  in 3 mos

43
continued

• Male Age 40 Chronic bronchitis and underwent
  acupuncture treatment for 1 month. Stopped taking
  pharmacology drugs. Started drinking mega doses
  of chaga daily. Persistent cough stopped within 1
  month
• Male Age 54 Type 2 Diabetic. Started low dosage
  of chaga for 3 months and then increased to 3
  grams. Cholesterol levels dropped considered
  within 6 months
• Male Age 56 Diagnosed with prostrate cancer.
  Started drinking chaga but no effect in first
  month. Over time, pain subsided and within 6
  months, cancer cells into remission
• Male Age 16 Severe dermatology and pimples.
  Considered laser surgery and botox treatment.
  Instead started drinking 2 g chaga daily and
  within 2 months, most of the pimples disappeared.

44
continued

• Female Age 53 High blood pressure dropped from
  170/140 to 130/80 in6 months after daily chaga
  intake.
• Male Age 58 Severe constipation. Changed diet
  constantly to eliminate meat, breads, sugars.
  Started drinking 3 g chaga daily, problem
  disappeared in 4 mos.
• Female Age 65 Started chaga in conjunction with
  stomach cancer chemotherapy treatment. Atypical
  symptoms were not prevalent.
• Male Age 9 Diagnosed with leukemia but family
  could not afford the 80,000 treatment. Instead
  reverted to chaga and problems into remission
  within 2 years
• Female Age 44 Severe facial and skin eczema.
  Started drinking 3 g chaga daily and problems
  disappeared in 3 months

45
SUMMARY

• Amongst all the higher edible
• medicinal mushrooms,
• Siberian Chaga is one of
• the most potent species and
• a very cost effective natural remedy for a wide
  array of immune or hormone related symptoms.
• The Siberian species function as well, or more
  effective, than the best Lingzhi grades for
  strong immune enhancement.
• The wild and natural Chaga species are quite
  distinguishable but invariably there will be a
  supply issue as more firms enter this market.
  Predicted trend to artificial cultivation similar
  to Lingzhi, Agaricus, Maitake and other well
  known medicinal mushrooms.

46
KEY QUESTION CONFRONTING US

• Why do some medicinal mushrooms work better than
  others? is a question that requires further
  clinical evaluation
• The pharmacology approach is to patent a single
  compound, sell it for a lot of money and hope it
  was the right ONE you need
• The TCM approach combines complementary or
  natural compounds to reach equilibrium balancing
• Hence a strong RD need to move closer towards
  each other to result in novel therapies and
  discovery of new drugs