2005 BristolMyers Squibb Company Overview

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(No Transcript)
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Agenda

• Company Overview
• Why Bristol-Myers Squibb?
• University Programs
• Q A

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Our Mission ...
To extend and enhance human life by providing the
highest-quality pharmaceutical and related health
care products.
We Pledge ...
To our patients and customers, to our employees
and partners, to our shareholders and neighbors,
and to the world we serve to act on our belief
that the priceless ingredient of every product is
the honor and integrity of its maker.
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Pharmaceuticals
Please see accompanying Full Prescribing
Information, including boxed WARNINGS for
Abilify, Videx and Videx EC, and boxed WARNING
for Avapro and Avalide regarding use in
pregnancy.
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Disease Areas of Significant Need

• Affective(Psychiatric)Disorders

Alzheimers / Dementia
Atherosclerosis /Thrombosis
Diabetes
Hepatitis
Oncology
Rheumatoid Arthritis Related Diseases
Solid Organ Transplant Rejection
HIV / AIDS
Obesity
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www.meadjohnson.com
A World Leader in Infant and Child Nutrition
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www.convatec.com
A World Leader in Ostomy Wound Therapeutics
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www.bmsmi.com
Please see Important Safety Information for
Cardiolite and Definity on slide 47and
accompanying Full Prescribing Information or
visit www.bmsmi.com/pis.htm.
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A Health Care Leader for the Future
Bristol-Myers Squibb is transforming itself
through...

• Focus
• Areas of significant unmet medical need
• A new business model
• Investing for growth
• Innovation
• Developing innovative therapies
• Renewing our company culture
• Compassion
• Expanding access
• Corporate philanthropy

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Why Bristol-Myers Squibb?
Compassion
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Compassion through Corporate Philanthropy
The Bristol-Myers Squibb Foundationseven areas
of focus

• Global HIV/AIDS
• Health education
• Womens health
• Science education
• Product donations
• Freedom to Discover Unrestricted Grants Program
• Employee contributions and community grants

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www.securethefuture.com
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For the third consecutive year,Bristol-Myers
Squibb will team up with cancer survivor and Tour
de France champion Lance Armstrong to sponsor
the Tour Of Hope A cross-country journey of
20 cyclists whose goal is to raise awareness
about cancer research and clinical
trials. September 29 October 8, 2005
www.tourofhope.org
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Building a Culture of Innovation and Performance
A Diverse Work Force

• We seek...
• Top talent with diversity ofbackground and
  experience
• We offer...
• Career development and advancement opportunities
• Performance Management System that rewards
  results and behaviors
• Employee Affinity (Networking) Groups
• World class Work / Life programs and services

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University Programs
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Program Overview
Technical Operations University Programs provides
participating interns and co-ops with the
opportunity to Learn about Bristol-Myers
Squibb and the pharmaceutical industry
Gain real world industry experience Work on
significant projects Demonstrate business and
technical skills Be considered for potential
full-time openings Participate in
developmental training Network throughout the
company
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Program Requirements

• Degree in designated field of study /
  coursework
• Technical Competency
• 3.0 GPA
• Rising Year in School (Sophomore, Jr., Sr., MS,
  MBA,
• Ph.D.)
• Must be enrolled in classes semester during or
  after the
• program
• Full time employment / Associate Program
  Prospect
• Extra-Curricular Activities
• Other Experiences (Work, Co-op, intern, etc)
• Demonstration of Core BMS Behaviors
• Professional Association Affiliation a plus

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Program Expectations

• Your Experience will include
• Meaningful Assignments
• Training
• Networking Opportunities
• Lunch Learn
• Presentations
• Socials (BBQ, Trips, Games)
• Facility Tours
• Upper Level Management Exposure
• Mentorship

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2005-2006 Openings
Internships BioTechnology, Syracuse,
NY Engineering, Plainsboro, NJ Pilot Plant, New
Brunswick Process Development, Evansville / Mt.
Vernon, IN Global Engineering, Plainsboro,
NJ Quality Compliance, New Brunswick,
NJ Co-ops (Jan Jun Jun Dec) Supply Chain,
Plainsboro, NJ Packaging, New Brunswick,
NJ BioTechnology, Syracuse, NY Manufacturing
Technology / API, New Brunswick, NJ Syracuse, NY
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Bristol-Myers Squibb Syracuse Site
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Characteristics of Biologics
Chemical Biologics Size (M.W.) lt
500 20,000-200,000 Complexity
Low High Process Conditions
(Temperature/Pressure) High Ambient
Process Concentration Concentrate Dilute
Process Volume lt 8,000 L lt20,000 L Process
Steps Multiple chemical Complex
product reactions/isolations made by
cells Process Solvents
Organic Aqueous Isolation/Purification
Crystallization Chromatography Product
Definition Few simple
assays Many complex assays Process Changes
Equivalency Clinical trial
by assay
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Small Molecule vs. Biologics
Aspirin
Insulin, one of the simplest human proteins (843
atoms) made using biotechnology
Technology Review, December 2004
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Syracuse Biologics Overview

• Organizational Structure
• Biotechnology Development- Late stage biologics
  development
• Process Development, Scale-up, and Optimization
• Technical Support for Clinical and Commercial
  Biologics Manufacturing
• New Technology Development
• Process Validation and Validation Services
• Biotechnology Operations
• Manufacture of bulk biologics drug substance

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Multi-Disciniplinary Field
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Career Opportunities in Biologics
Seed/Inoculum (vials to 1,100 L)
Fermentation (4,000 L - 20,000 L)

Recovery/Purification

• Membrane technology
• Chromatography
• Product aggregation
• In-process monitoring
• Product quality

• Scale up
• Media preparation
• Process control
• In-process monitoring
• Product quality

• Cell line
• Growth media
• Genetic stability

• Microbiologists
• Cell Biologists
• Biochemical Engineers

• Analytical Biochemists
• Biochemical Engineers

• Chromatographers
• Protein Chemists
• Biochemical Engineers

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What We Look For In Employees

• Leads Strategically
• Builds Alignment
• Communicates Directly
• Drives Performance
• Collaborates
• Energizes Others
• Develops People

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Q A
Questions?