The Eye in Systemic Disease

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• The Eye in Systemic Disease

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The Eye in Systemic Disease

• Numerous conditions have eye symptoms associated
  with them
• Different parts of the eye are associated with
  different syndrome

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The Eye in Systemic Disease

• Structure of Talk
• Mind Map

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Pupillary Abnormalities
Amaurosis Fugax
Cataracts
Eye
Retinal vessel disease
Uveitis
CRAO
Abnorm Eye Movements
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Common Eye Problems
Cataracts
Eye
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Metabolic
CATARACTS
Other Systemic Diseases
Drug Induced
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DM
G6PD
Meta-bolic
CATARACTS
PFKD
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Metabolic
CATARACTS
Muscular Dystrophy
Other Systemic Diseases
NF 2
Derma-titis
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Metabolic
CATARACTS
Steroids
Other Systemic Diseases
Drug Induced
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Common Eye Problems
Pupillary Abnormalities
Amaurosis Fugax
Cataracts
Eye
Retinal vessel disease
Uveitis
CRAO
Abnorm Eye Movements
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Common Eye Problems
Eye
Uveitis
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Systemic Dis Syndromes
Uveitis
Infections
Infestations
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Systemic Dis Syndromes
Uveitis
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Behcets
Reiter's
Sarcoid
Ank Spond
Systemic Dis Syndromes
Uveitis
Crohn's Dis
UC
JCA
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Behcets
Reiter's
Sarcoid
Ank Spond
Systemic Dis Syndromes
Uveitis
Crohn's Dis
UC
JCA
Polyarthritis
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Behcets
Reiter's
Sarcoid
Ank Spond
Systemic Dis Syndromes
Uveitis
Crohn's Dis
UC
JCA
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Behcets
Reiter's
Sarcoid
Ank Spond
Systemic Dis Syndromes
Uveitis
Crohn's Dis
UC
JCA
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Sacro-iliitis (also spine)
Beh-cets
Reiter's
Sar-coid
Ank Spond
Systemic Dis Syndromes
Uveitis
Crohn's Dis
UC
UC
JCA
JCA
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Urethritis
Arthritis
Behcets
Reiter's
Sarcoid
Systemic Dis Syndromes
Ank Spond
Uveitis
Crohn's Dis
UC
JCA
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Overreaction of Immune System
Behcets
Reiter's
Sarcoid
Systemic Dis Syndromes
Ank Spond
Uveitis
Crohn's Dis
UC
JCA
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oral ulcers
Genital ulcers
Reiter's
Beh-cets
Skin Lesions
Sarcoid
Systemic Dis Syndromes
Ank Spond
Uveitis
Crohn's Dis
UC
JCA
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Behcets
Granulomas
Reiter's
Sarcoid
Unknown Aetiology
Systemic Dis Syndromes
Ank Spond
Uveitis
Crohn's Dis
UC
JCA
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Behcets
Reiter's
Sarcoid
Systemic Dis Syndromes
Ank Spond
Uveitis
Crohn's Dis
UC
JCA
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Systemic Dis Syndromes
Uveitis
Infections
Infestations
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Uveitis
Infections
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TB
Infections
Herpes Zoster
Candida
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Systemic Dis Syndromes
Uveitis
Infections
Infestations
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Uveitis
Infestations
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Toxoplasmosis
Infestations
Pneumocystosis
Toxocariasis
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Common Eye Problems
Pupillary Abnormalities
Amaurosis Fugax
Cataracts
Eye
Retinal vessel disease
Uveitis
CRAO
Abnorm Eye Movements
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Common Eye Problems
Eye
Abnorm Eye Movements
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Common Eye Problems
CVA
Abnorm Eye Movements
DM
Aneurysm
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Common Eye Problems
Pupillary Abnormalities
Amaurosis Fugax
Cataracts
Eye
Retinal vessel disease
Uveitis
CRAO
Abnorm Eye Movements
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Common Eye Problems
Eye
CRAO
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CRAO
Source of Emboli
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Common Eye Problems
Pupillary Abnormalities
Amaurosis Fugax
Cataracts
Eye
Retinal vessel disease
Uveitis
CRAO
Abnorm Eye Movements
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Common Eye Problems
Eye
Retinal vessel disease
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Diabetes Mellitus
Retinal vessel disease
Hypertension
Hypercholesterolaemia
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Diabetes Mellitus
Retinal vessel disease
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Background Retinopathy
Diabetes Mellitus
Maculopathy
Pre-prolif Retionopathy
Proliferative Retinopathy
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Background Retinopathy
Diabetes Mellitus
Maculopathy
Pre-prolif Retionopathy
Proliferative Retinopathy
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Dot Haemorrhages
Micro- aneurysms

• NORMAL eyesight
• -present in almost all who have had type 1
  diabetes for 20 years
• -present in nearly 80 percent of those with type
  2 disease for 20 years

Background Retinopathy
Hard Exudates
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Background Retinopathy
Diabetes Mellitus
Maculopathy
Pre-prolif Retionopathy
Proliferative Retinopathy
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Diabetes Mellitus
Pre-prolif Retinopathy
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Cotton Wool Spots
NORMAL EYESIGHT
Pre-prolif Retionopathy
Venous Irregularity
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Pre-prolif Retionopathy
REFER! 50 of patients progress to
proliferative retinopathy within 1-2 years
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Background Retinopathy
Diabetes Mellitus
Maculopathy
Pre-prolif Retionopathy
Proliferative Retinopathy
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Diabetes Mellitus
Proliferative Retinopathy
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NVD
Neo- vascularisation
NVE
Proliferative Retinopathy
NORMAL EYESIGHT, but threatened....
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Proliferative Retinopathy
REFER!
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Background Retinopathy
Diabetes Mellitus
Maculopathy
Pre-prolif Retino-pathy
Proliferative Retinopathy
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Diabetes Mellitus
Maculopathy
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Early and Diffuse
Maculopathy
EYESIGHT AFFECTED
Severe and Ischaemic
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REFER!
Maculopathy
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Diabetes Mellitus
Retinal vessel disease
Hyper-tension
Hypercholest- erolaemia
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Retinal vessel disease
Hyper-tension
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Grade I
Hypertension
Grade II
Grade IV
Grade III
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Grade I
Hypertension
Grade II
Grade IV
Grade III
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Grade I
Hypertension
Grade II
Grade IV
Grade III
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Grade I
Hypertension
Grade II
Grade IV
Grade III
Cotton Wool Spots
Haemorr- hages
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Grade I
Hypertension
Grade II
Grade IV
Grade III
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Silver Wiring
Grade I
Hypertension
Grade II
Grade IV
Grade III
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Grade I
Hypertension
Grade II
Grade IV
A-V Nipping
Grade III
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Grade I
Hypertension
Grade II
Grade IV
Grade III
Cotton Wool Spots
Haemorr- hages
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Grade I
Papill- oedema
Hypertension
Grade II
Grade IV
Grade III
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Diabetes Mellitus
Retinal vessel disease
Hyper-tension
Hypercholest- erolaemia
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Common Eye Problems
Pupillary Abnormalities
Amaurosis Fugax
Cataracts
Eye
Retinal vessel disease
Uveitis
CRAO
Abnorm Eye Movements
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Common Eye Problems
Pupillary Abnormalities
Amaurosis Fugax
Cataracts
Eye
Retinal vessel disease
Uveitis
CRAO
Abnorm Eye Movements
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Amaurosis Fugax painless, transient
(secs/ mins), partial or complete
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Neourologic
Embolic
Embolic
Amaurosis Fugax
Vasospastic/ Haemodynamic
Ocular
Idiopathic
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Optic Neuritis (MS)
Embolic
Embolic
Neuro-logic
Migraine
Amaurosis Fugax
Vasospastic/ Haemodynamic
Ocular
Idiopathic
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Neourologic
TIA (cardiac/ carotid/ other)
Embolic
Amaurosis Fugax
Vasospastic/ Haemodynamic
Ocular
Idiopathic
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Embolic
Embolic
Neuro-logic
Amaurosis Fugax
Vasospastic/ Haemo-dynamic
Ocular
Idio-pathic
Temp Arteritis
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Common Eye Problems
Pupillary Abnormalities
Amaurosis Fugax
Cataracts
Eye
Retinal vessel disease
Uveitis
CRAO
Abnorm Eye Movements
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Common Eye Problems
Pupillary Abnormalities
Amaurosis Fugax
Cataracts
Eye
Retinal vessel disease
Uveitis
CRAO
Abnorm Eye Movements
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Horner's Syndrome
Pupillary Defects
CVA/SOL
Adies Pupil
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Common Eye Problems
Pupillary Abnormalities
Amaurosis Fugax
Cataracts
Eye
Retinal vessel disease
Uveitis
CRAO
Abnorm Eye Movements