The Stop TB Partnership Task Force on Retooling Update for the Working Groups Annual Meeting

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The Stop TB Partnership Task Force on
RetoolingUpdate for the Working Groups Annual
Meeting

Vinand Nantulya Nina Schwalbe, co-chairs of
Task Force
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Pipeline Noted
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Rationale for Task force

• As noted by Global Plan in previous slide a
  steady stream of innovations is coming beginning
  as early as 2007
• But major challenges lie ahead in adopting these
  tools
• Rapid adoption will require planning and
  preparedness

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Task Force on Retooling

• Created by the Coordinating Board in Assisi,
  November 2005 to help prepare the TB community
  for the adoption, introduction and implementation
  of new/improved diagnostics, drugs, and vaccines

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Terms of Reference (1)

• Develop a framework/guideline
• Consolidate information from tools working groups
  (timelines, milestones, etc)
• Create dialogue among stakeholders
• Facilitate mobilization of resources

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Terms of Reference (2)

• Consolidate lessons learned from other
  innovations
• Fast track incorporation in WHO and national
  policy
• Enhance communication among working groups
• Facilitate introduction of operations research
  and generate evidence around new tools

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Composition of Task Force

• Working group members, designated by chairs
• Key sub groups (laboratory, GDF, poverty)
• National TB Program Managers from high- burden
  countries
• WHO Stop TB Department and other relevant WHO
  departments
• Stop TB Partnership Secretariat (as secretary)

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Activities to date

• July face to face meeting in Geneva
• Agreement to produce framework document
• Commissioning of MSH to draft document, under
  guidance from task force core group (weekly
  teleconferences)
• Completion of draft guide for presentation to
  Coordinating Board in November 2006

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Objectives of the guide

• Provide a common framework to discuss the
  adoption of new tools for TB control
• Identify some key issues that need to be
  addressed to accelerate the adoption and
  implementation and
• Provide guidance on what actions are needed for
  adoption, access and proper use by the community.

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Key elements (1)Availability of tools for
adoption

• For diagnostics availability is after the
  demonstration studies
• For drugs and vaccines it is after Phase III
  clinical trials

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Key elements (2) The document

• Identifies key challenges to adoption and
  implementation of new technologies
• Proposes key principles to facilitate appropriate
  and timely adoption and implementation
• Provides overview of technical and operational
  considerations for global and national levels.

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Key elements (3) Annexes

• Overview of selected new medicines, diagnostics
  and vaccines in the pipeline
• Listing of key actions for the adoption and
  implementation of each technology category
• Illustrative generic timeline for adoption,
  introduction and implementation
• List of key readings that provide more detailed
  discussions of the issues and road maps.

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Next steps

• Expansion of task force membership
• Additional national TB program managers
• Members of WHO essential medicines policy group
• Additional members of ACSM, DOTS and DOTS
  expansion working groups
• Dissemination of framework document
• Development of additional documents and
  guidelines
• Guidance on stakeholder engagement
• Updated pipeline chart
• Retooling monitoring and evaluation framework
• Illustrative timelines for post regulatory
  process
• Recommendations for the introductions of specific
  new tools

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Task Force Members

• Rachel Bauquerez (secretariat)
• Leopold Blac
• Saidi Egwaga
• Sara England (secretariat)
• Ulrich Joseph Furth (core committee)
• Christy Hanson (core committee)
• Barbara Laughon
• Lindiwe Mvusi
• Aziz Mohammed
• Vinand Nantulya (co-chair, core committee)

• Ikushi Onazaki
• Philip Chukwuka Onyebujoh (core committee)
• Andrew Ramsey (core committee)
• Nina Schwalbe (co-chair, core committee)
• Birte Holme Sorensen
• Javid Syed (core committee)
• Karen Weyer
• Patrick Zuber
• Carole Francis

MSH team Naranjan Konduri, David Lee, Evan Lee,
Helena Walkowiak