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Pharmaceutical Dosage ModulesPower Point

Presentation

Instructions

- Be sure to work through the problems before

attempting to watch the lecture tapes. - After working through the problems as much as you

can, watch the tapes for the necessary steps

needed to solve the problems correctly. - Remember practice makes perfect when working

dosage problems

Good Luck with the Modules!!!

- Dr. R. R. Espinosa, R.Ph., Pharm. D.
- Pharmacology Dosage Modules I-V

Dosage Modules

- Module 1 Dimensional Analysis
- Module 2 Basic Dosage Calculations
- Module 3 Reconstitution
- Module 4 Basic IV Dosage

Calculations - Module 5 Advanced Intravenous

Calculations

Pharmaceutical Dosage Module 1 Dimensional

Analysis

Dimensional Analysis

- Given Quantity the beginning point of the

problem - Conversion Factors- Equivalents necessary to

convert between systems of measurement and to

allow unwanted units to be cancelled from the

problem

Dimensional Analysis

- Unit Path the series of conversions necessary

to achieve the Wanted Quantity - Wanted Quantity the answer to the problem

Converting Within and Between Systems of

Measurement

System of Measurement

- Household tsp, gtt, T, c
- Apothecary gr, dr, oz
- Metric ml, mg, g, l

Conversion Problems

- 350 mg _______g
- 0.016 g _______mg
- 0.16 kg _______lb
- 8 mg _______gr
- 0.07 mg ______mcg
- 500 ml _______L
- 45 gr _______mg

Conversion Problems

- issgr _________g
- xx drams _____ml
- 75 ml ________oz
- vss oz _______ml
- 9 g __________gr
- 102 lb _______kg
- 3 tsp ________ml

Conversions problems

- 3 ml _________Minims
- 4 drams ______oz
- iv gr _________mg
- 25 L ______ml
- 1/300 gr ______mg
- 200ml ________tsp
- 6 tsp _________T

Answers to problems Not covered on lecture tape

- 4drams0.67oz
- 4 gr240mg
- 25L25000ml
- 200ml40tsp
- 6tsp2T

Pharmaceutical Dosage Module 2 Basic Dosage

Calculations

Dosage Calculations

- The doctor orders a patient to receive Daypro

1200mg q am and pm. The stock supply is

600mg/tab. How many tablets will the patient

receive for the correct dose? - -Given Quantity -Dose on Hand
- -Wanted Quantity -Answer

(No Transcript)

Dosage Calculations

- The doctor orders a patient to receive Daypro

1200mg q am and pm. The stock supply is

600mg/tab. How many tablets will the patient

receive for the correct dose? - -Given Quantity -Dose on Hand
- -Wanted Quantity -Answer

Dosage calculations

- A patient is to receive Doxycycline 5 gr po

qid for infection. The stock supply is

100mg/caps. How many capsules will the patient

receive for the correct dose? - -Given Quantity -Dose on Hand
- -Wanted Quantity -Answer

(No Transcript)

Dosage calculations

- A patient is to receive Doxycycline 5 gr po

qid for infection. The stock supply is

100mg/caps. How many capsules will the patient

receive for the correct dose? - -Given Quantity -Dose on Hand
- -Wanted Quantity -Answer

Dosage Calculations

- Patient is to receive 0.5 g of Zocor q hs for

cholesterol. The stock supply is 20mg/tab. How

many tablets will the patient receive for the

correct dose? - -Given Quantity -Dose on Hand
- -Wanted Quantity -Answer

(No Transcript)

Dosage Calculations

- MD orders the client to have 1/8 gr of

Estratab qod. The stock supply is 1.25 mg

tablet. How many tablets will the patient

receive for the correct dose? - -Given Quantity -Dose on Hand
- -Wanted Quantity -Answer

(No Transcript)

Dosage Calculations

- Patient is to receive 70 mg IM stat of

Solu-Medrol. The stock supply is 125mg/2ml. How

many mls is the patient going to receive for the

correct dose? - Given Quantity -Dose on Hand
- Wanted Quantity -Answer

Dosage Calculations

- Dr orders Trimox 0.5 g q 6 h for infection.

The stock supply is 250mg/5ml. The total volume

is 100ml. How many mls will the patient receive

for the correct dose? How may teaspoonfuls will

the patient receive for each dose? - Given Quantity -Dose on Hand
- Wanted Quantity -Answer

(No Transcript)

Dosage Calculations

- Patient is to receive Atropine 0.2mg Sub Q

stat, then 0.15 mg every 6 hours as needed. The

stock supply is 400mcg/ml. How many mls will

the patient receive for the first dose? How many

mls will the patient receive on each subsequent

dose? - Given Quantity -Dose on Hand
- Wanted Quantity -Answer

Dosage Calculations

- Patient is to receive Gentamicin ¼ gr IV q 4 h

for infection. The stock supply is 15mg/ml. How

many mls will the patient receive for the

correct dose? How often is this medication

given? What is the route of administration? - -Given Quantity -Dose on Hand
- -Wanted Quantity -Answer

Pharmaceutical Dosage Module 3

Reconstitution

Reconstitution

- The doctor orders Ancef 750mg IM q 8 h. The

stock supply is a 1.0 g vial of powdered Ancef.

Directions say to reconstitute with 2.5 ml of

water to produce a total volume of 3 ml. - How many mls will you give to the patient for

the correct dose? - How many mgs will the patient receive for the

correct dose in 24 hours(1 day)? - How many grams will the patient receive in 24

hours?

Reconstitution

- The doctor orders Ancef 750mg IM q 8 h. The

stock supply is a 1.0 g vial of powdered Ancef.

Directions say to reconstitute with 2.5 ml of

water to produce a total volume of 3 ml. - How many mls will you give to the patient for

the correct dose? - How many mgs will the patient receive for the

correct dose in 24 hours(1 day)? - How many grams will the patient receive in 24

hours?

Reconstitution

- Patient is to receive 3 g of Ampicillin to be

added to a 1000ml D-5-W IV q 8 h. The stock

supply is a 10,000mg Ampicillin vial. Directions

say to reconstitute with 9.8 ml of NS to yield

500mg/ml. - How many mls of Ampicillin will you add to the

IV bag for the correct dose?

Reconstitution

- Patient is to receive 3 g of Ampicillin to be

added to a 1000ml D-5-W IV q 8 h. The stock

supply is a 10,000mg Ampicillin vial. Directions

say to reconstitute with 9.8 ml of NS to yield

500mg/ml. - How many mls of Ampicillin will you add to the

IV bag for the correct dose?

Reconstitution

- Patient is to receive Nafcillin 5 gr IM q 6

hours for infection. The stock supply is a 2 g

vial. The directions say to add 6.6 ml of

sterile water to yield 250mg/ml. The total

volume in the vial is 8ml. - How many mls will the patient receive for the

correct dose? - How often is the patient receiving the medication?

Reconstitution

- Suprax 0.4g po q d for 12 days is order for a

patient for infection. The stock supply is a 2 g

bottled powder. The directions says to

reconstitute with 69 ml of water. This will

provide 100mg/ml. - How many mls will the patient receive for one

dose? - What would be the total mls for the entire dose?

Reconstitution

- Client is to receive Cephalexin 2 g IV qid

for infection. The stock supply is a 2 gram

vial. Directions say to add 5ml of sterile water

for injection, this will yield a concentration of

160mg/ml. - How may mls will the patient receive for the

correct dose? - How often is the patient to receive this dose?

Reconstitution

- MD orders Timentin 8 gr IV tid. Timentin is

available in a 3.1g powder. Directions say to

use 13 ml of sterile water for injection. The

concentration will be approximately 200mg/ml. - How many mls will be administered for the

correct dose?

Pharmaceutical Dosage Module 4 Basic IV

Dosage Calculations

Calculating Intravenous Flow Rates

- Electronic
- vs.
- Manual Infusion Devise

Electronic

- IV flow rate pump delivers volume in ml/hr
- Nurses responsibility to program the pump
- Amount of fluid/over period of time

Manual

- IV flow rate must be determined in gtts/min
- Nurses responsibility to count the number of

drips that drop in a minute into the drip chamber - The IV tubing provides the drop factor, which is

calibrated in drops/ml

Basic IV Calculations

- A client on an infusion pump is to receive an

antibiotic in 50 ml 0.9 NS over 30 minutes.

What is the flow rate in ml per hour? - Given Quantity
- Wanted Quantity
- Answer

Medication involving Intravenous pump

- A client on an infusion pump is to receive

500ml of R/L in 12 hours. What is the flow rate

in ml per hour? - Given Quantity
- Wanted Quantity
- Answer

Medication involving Intravenous pump

- The doctor orders 100ml of D-5-W to infuse in

20 minutes q 4 hours. What is the flow rate in

ml/hr? - Given Quantity
- Wanted Quantity
- Answer

Medication Problem Involving a Drop Factor

- The doctor orders 150 ml of D5W to be infused

over 45 minutes q 4 hours. The drop factor is 20

gtts per ml. What is the flow rate in drops per

minute? - Given Quantity
- Wanted Quantity
- Drop factor
- Answer

Basic IV Calculations

- The doctor orders 250 ml of D-5-W IV q 3 hours.

The drop factor is 20 gtts/ml. What is the flow

rate in gtts/min? What is the flow rate in

ml/hr? - Given Quantity
- Wanted Quantity
- Drop Factor
- Answer

Pharmaceutical Dosage Module 5 Advanced

Intravenous Calculations

- The MD orders 10,000 units of Penicillin to be

added to the IVPB of 100ml of NS to infuse in 45

minutes every 6 hours. Stock supply is a vial

containing 2,000,000 units of Penicillin.

Directions says to reconstitute with 9.8 ml to

yield a 10 ml total volume. The drop factor for

the IVPB is 15 gtts/ml. - How many mls of penicillin will you add to the

IVPB for the correct dose? - What is flow rate in gtts per min for the IVPB?
- What is the flow rate in ml per hour?

- The MD orders 10,000 units of Penicillin to be

added to the IVPB of 100ml of NS to infuse in 45

minutes every 6 hours. The stock supply is a

vial containing 2,000,000 units of Penicillin.

Directions says to reconstitute with 9.8 ml to

yield a 10 ml total volume. The drop factor for

the IVPB is 15 gtts/ml. - How many mls of penicillin will you add to the

IVPB for the correct dose? - What is the flow rate in gtts per min for the

IVPB? - What is the flow rate in ml per hour?

Advanced Intravenous Calculations

- Dopamine 2mcg/kg/min is order for a patient.

The pharmacy sends an IV bag labeled Dopamine

400mg/ 250 ml D5W. The client weighs 150 lbs. - -What is the flow rate in mls per hour?
- Given Quantity -Dose on Hand
- Wanted Quantity -Answer

Advanced Intravenous Calculations

- MD orders Nipride 3mcg/kg/min. The pharmacy

sends a bag labeled Nipride 50mg/ 250 ml of NS.

The drop factor is 15 gtts/ml. The patient

weighs 110 lbs. - -Calculate the ml/hr to set the IV pump?

-What is the flow rate in gtts/min? - Given Quantity -Dose on Hand
- Wanted Quantity -Answer

Advanced Intravenous Calculations

- Dobutamine 500mg in 250 ml D5W to infuse at

10mcg/kg/min. The client weighs 250 lbs. - -What is the flow rate in ml/hr?

-What is the flow rate in

drops/minute with a drop

factor of 60 gtts/ml? - Given Quantity -Dose on Hand
- Wanted Quantity -Answer

Conclusion

- I hope this has helped you achieve yours goals of

understanding different types of dosage

calculations that you will encounter in this

class and on into your careers. - Good Luck, Allied Health Science Faculty

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