Areas of Interest and Undergraduate Research Opportunities

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Areas of Interest and Undergraduate Research
Opportunities

• Donald E. Mencer (mencer_at_wilkes.edu)Department
  of Chemistry, Wilkes University,
• 84 W. South Street, Wilkes-Barre, PA 18766
• Junior Seminar Presentation
• 19 February 2010

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Three general types of projects

• Linked to a course (usually this has been in
  CHM343 laboratory)
• Projects generated largely due to an interest
  area of a student
• Research loosely related to my interests
• instrumental applications to investigate chemical
  systems
• materials synthesis and characterization
• noncovalent chemical interactions

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Proton NMR Quantitative Analysis
Beefeater Gin
K.Rublein, First Annual NMR Conference, 17
September 2005, Bucknell Univ., Lewisburg, PA
and MARM2005, May 22-25, 2007, Rutgers
University, Piscataway/New Brunswick, NJ.
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Proton NMR Quantitative Analysis
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1H NMR Qualitative Analysis
Ibuprofen, C13H18O2 10 magnetically unique C 8
magnetically unique H
Steve P. Lee, 230th National Meeting of the ACS,
Washington, D.C. August 28-Sept. 1, 2005
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1H NMR Qualitative Analysis
Ibuprofen in CDCl3 Sum of normalized 1H integrals
18.08
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13C NMR Qualitative Analysis
Ibuprofen in CDCl3
Solvent peaks
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Polarization Transfer Methods in NMR
DEPT for Ibuprofen
q 135
q 90
q 45
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2D Methods COSY of Ibuprofen
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Isolation of piperine from black pepper (and more
. . . Natalie Harvey)
Piperine 1-(2E,4E)-5-(1,3-benzodioxol-5-yl)pent
a-2,4-dienoylpiperidine

• two double bonds four isomers
• 2E, 4E
• 2E, 4Z
• 2Z, 4E
• 2Z, 2Z

William W. Epstein, David F. Netz, and Jimmy L.
Seide1 J Chem Ed., 70 (7) 1993 598-599
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Isolation of Piperine from black pepper
Three major peaks (and one minor) are isomers of
piperine.

Library mass spectrum of piperine
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Extraction, Derivatization, and Gas
Chromatography/Mass Spectra of Antineoplastics
(David Willingham)
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Extraction, Derivatization, and Gas
Chromatography/Mass Spectra of Antineoplastics
(David Willingham)
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Trace Analysis of Pesticides in Malt Beverages by
Capillary Gas Chromatography with Mass
Spectrometry (Paul Sarnoski)
Calibration curve anthracene in malt beverages
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Trace Analysis of Pesticides in Malt Beverages by
Capillary Gas Chromatography with Mass
Spectrometry (Paul Sarnoski)
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Ionic Liquids interesting solvent systems
ethyl ammonium nitrate (EAN)
tributyl ammonium nitrate (TBAN)
propyl ammonium nitrate (PAN)
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Solvatochromatic dyes in ionic liquids

• Riechardts dye 2,6-diphenyl-4(2,4,6-triphenyl-N
  -pyridino)-phenolate.

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EThcNA / ?max ET 28591(kcal/mol) / ?max
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The Solubility Constants Sparingly Soluble Salts
in Ionic Liquids (Faith Wydra)
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The Solubility Constants Sparingly Soluble Salts
in ethyl ammonium nitrate (Faith Wydra)
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Other Projects . . .

• Materials research
• (Tim Oswald, Bri Bertoni, and Dave Watkins)
  Electroless coating of various materials with
  various metals and alloys
• (Amanda Derr) Bio-Functional Nano-Coating
• KIZ Life Sciences Collaborative (2006-2007) -
  Bio-Functional Nano-Coating
• KIZ Life Sciences Collaborative (2007-2008) -
  Smart light weight flexible multilayer cable
  design manufacturing
• Instrument projects
• (Jacob Watt Groom) Interfacing a GC using
  LabView (Dr. Trujillo on-sight advisor)

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Other Projects . . .

• Research colleagues at Lamar University,
  Beaumont, TX
• Matrix isolation studies of photochemical smog
  components
• studies of electrocoagulation
• copper oxidation investigations
• and fuel cell catalysis work (more nanoclay work)
• Sabbatical biophysical peptide chemistry with
  the DeGrado group at UPenn
• and more . . .

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NMR and FT-IR studies of polyol interactions in
water (Shauna Anderson)
D-mannitol
sorbitol
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D-Mannitol
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D-Mannitol
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D-Mannitol
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Sorbitol
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Sorbitol
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Sorbitol
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Acknowledgements

• Students from CHM 344 (now 343)
• 2005 Mark Hunter, Ann Leotaud, Deana Mikhalkova,
  Tim Oswald, Renee Peters, and Todd Ronco
• 2006 Thomas Dougal, Nicholas Durham, Christine
  Ervin, Justin Nace, Lauren Pantzar, Aniello
  Tambasco, David Watkins
• 2007 Brynn Beaver, Adam Butler, Kenneth Green,
  Lauren Macri, Samantha Payne, Elise Serembus,
  Jerry Shovlin, James Thomas, Julie Wagner, Kate
  Willis, Faith Wydra
• 2008 Amanda Derr, Justin Huff, Amanda Karaffa,
  Ross McGlynn, Melissa Mendolia, Naseem Mian,
  Michael Simko, Aaron Sulla, Kyle Ungvarsky, Jason
  Woloski, Michelle Zaleski
• 2009 Natalie Harvey, Caela Bernecker, Troy
  Hinkley, Justin Spott, Heather Shoemaker, Veeraj
  Jadeja, Michael Pauley, Michael Simko, Casey Grow
• Wilkes University
• Lab space, supplies, instrumentation, and partial
  travel support

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Resources

• B. Esselman and D.E. Mencer, in a chapter
  entitled Inclusion of NMR in High School
  Chemistry Two Approaches, Modern Nuclear
  Magnetic Resonance in Undergraduate Education,
  editors D. Rovnyak, R.A. Stockland and S. P. Lee,
  (Oxford University Press, 2007) pp 77 90.
• K.Rublein, First Annual NMR Conference, 17
  September 2005, Bucknell Univ., Lewisburg, PA and
  MARM2005, May 22-25, 2007, Rutgers University,
  Piscataway/New Brunswick, NJ.
• Innovative Experiments Using Permanent Magnet
  NMR Spectrometers in HS and Undergraduate
  Courses 230th National Meeting of the American
  Chemical Society (Fall 2005 Meeting), Washington,
  D.C. August 28-Sept. 1, 2005
• D. E. Mencer Permanent magnet FT-NMR
  spectrometers Versatile tools for undergraduate
  instruction and high school outreach
• S.P. Lee Integration of FT-NMR spectroscopy in
  the organic chemistry curriculum at Roosevelt
  University.
• W.W. Epstein, D.F. Netz, and J.L. Seide1 J Chem
  Ed., 70 (7) 1993 598-599
• D. Riccio, D.C. Wood, and J.M. Miller, J Chem Ed
  85 (7) 2008 965-968

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Thank you and . . . .

• Questions?

26 March 2009