Centers of Biomedical Research Excellence COBRE Phase III: Transitional Centers

1
Centers of Biomedical Research Excellence (COBRE)
Phase III Transitional Centers

• National Center for Research Resources Council
• February 12, 2009
• W. Fred Taylor, Ph.D.
• IDeA Program Director
• National Center for Research Resources
• National Institutes of Health
• U.S. Department of Health and Human
  Services

2
Centers of Biomedical Research Excellence (COBRE)

• Background
• COBRE program launched in fiscal year 2000
• To expand and develop biomedical faculty research
  capability
• To enhance research infrastructure including core
  facilities
• Currently two sequential 5 year phases
• Phase I (COBRE Type 1) To develop research
  infrastructure and provide junior (new)
  investigators mentoring and project funding so
  they may compete for independent research support
• Phase II (COBRE Type 2) To further develop
  research infrastructure and develop a strong
  critical mass of investigators (new, early stage
  and established) with shared scientific interests

3
Centers of Biomedical Research Excellence (COBRE)
New Applications Phase I

• Purpose
• To build multidisciplinary research centers with
  a thematic scientific focus at doctoral
  institutions or research institutes
• Center Characteristics
• Led by an established investigator, funded by
  NIH, NSF or other comparable Federal or private
  sector source
• At least 3 research sub-projects, all supervised
  by junior investigators
• A clear plan for mentoring, career development
  and graduation and replacement of junior (new)
  investigators
• Long-term plans for developing and sustaining the
  center, investigators, collaborations, and
  physical infrastructure

4
Centers of Biomedical Research Excellence (COBRE)
Competing Continuation Applications Phase II

• Purpose
• To obtain continuation funding to build an
  independent multidisciplinary research center
  that can compete successfully for NIH funding
  from other sources
• Center Characteristics
• Comprising 3 to 5 research sub-projects
• Each sub-project supervised by a qualified
  investigator (eligibility expanded relative to
  type 1 COBRE)

5
Centers of Biomedical Research Excellence (COBRE)
Phase III Transitional Centers

• Purpose
• To maintain research cores essential for the
  conduct of basic, clinical and translational
  research
• To sustain a collaborative, multidisciplinary
  research environment by supporting mentoring and
  training components.
• Center Characteristics
• Administrative Core (mentoring and training
  components)
• Core resources including core supplies, service
  contracts and core management
• Equipment upgrades and replacement

6
Centers of Biomedical Research Excellence (COBRE)
Phase III Transitional Centers

• Program respectfully requests concept clearance
  of this proposal by Council.

7
Institutional Development Award ProgramDivision
of Research Infrastructure
Opportunities for Inclusion