Modifiable Risk Factors Associated with Adverse Cardiovascular and Renal Events in Chronic Kidney Di

1
Modifiable Risk Factors Associated with Adverse
Cardiovascular and Renal Events in Chronic Kidney
Disease

• Hypertension
• Albuminuria
• RAAS
• Dyslipidemia
• Anemia

• Smoking
• Glycemia
• Calcium-phosphorus product
• Others

Sarnak et al. Hypertension. 2003421050-1065.
2
Statin Treatment Results in Reduced CV Events for
All Subgroups of Patients ASCOT
Risk Ratio
Patient Group

• 19,342 patients with hypertension
• Randomized to atorvastatin or placebo
• Primary end point fatal CHD or nonfatal MI

Nondiabetes
Noncurrent smoker
Nonobese
No LVH
Male
No previous vascular disease
Renal dysfunction
No renal dysfunction
All patients
0.5
1.0
1.5
Atorvastatin Better
Placebo Better
Area of squares is proportional to the amount of
statistical information.ASCOTAnglo-Scandinavian
Cardiac Outcomes Trial MImyocardial
infarction.Sever et al. Lancet.
20033611149-1158.