Title: DEVELOPMENT OF STRATEGIES FOR PREVENTION OF CHRONIC KIDNEY DISEASE RELEVENT TO DIFFERENT REGIONS AND
1DEVELOPMENT OF STRATEGIES FOR PREVENTION OF
CHRONIC KIDNEY DISEASE RELEVENT TO DIFFERENT
REGIONS AND COUNTRIES
- ROBERT C ATKINS
- BELLAGIO, MARCH 2004
2DIALYSIS PATIENTS WORLD-WIDE (1996)
Schena, Kidney Int (Suppl 74), 2000
3Incidence of Diabetes in E.S.R.F Australia 1980
- 2000
Number of Diabetics
Number of New Patients
Year of Entry
4CAUSES OF ESRD IN THE USA
140
Diabetes
120
100
80
Hypertension
Incidence rates (x million population)
60
Glomerulonephritis
40
20
Cystic kidney
0
1990
1992
1994
1996
1998
USRDS, 2000
- Diabetes and hypertension are the main causes for
ESRD in the USA - The proportion of ESRD patients with diabetic
nephropathy is higher in the USA than in Europe.
However, diabetic nephropathy is the most rapidly
growing cause of ESRD in European countries
5AUSDIAB RESULTS
- 7.2 with diabetes
- (3.6 known and 3.6 newly diagnosed)
- 16.1 with impaired glucose metabolism
- 60 overweight or obese
- 61.3 with high cholesterol (7.3 on treatment)
- 29 with high blood pressure (14 on treatment)
6PREVALENCE OF RENAL ABNORMALITIES
- 1. Haematuria gt10x106/L 4.6
2. Proteinuria 2.4 UPUCgt0.2
mg/mg3. Renal Impairment 11.2 calculated
GFR lt60 mls/min No abnormality 82 At least
one abnormality 18 Multiple abnormalities
2
7PREVALENCE OF TYPE 2 DIABETES IN ASIA AND PACIFIC
Age-standardised to Segis world population
35-64 years except ³40 30-59 30-69
20-64 40-69
8THE GLOBAL BURDEN OF DIABETES (2000-2025)
38.4
37.5
30.7
18.6
24.5
57.2
16.7
25
102
22.8
47
21.8
150
9.1
39.3
140
18.2
0.4
0.7
64
116
In million subjects
World
Developed Count.
Developing Count.
2000 2025
154 m 300 m
55 m 72 m
99 m 228 m
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