Rheumatic Fever Aschoff Body edema and Monos

1
Rheumatic Fever -- Aschoff Body -- edema and Monos
2
Aschoff Body -- binucleate cell
3
Rheumatic Mitral Valvulitis -- thickened chordae
tendineae and opaque valve
4
Fish mouth valve -- rigid -- Mitral Stenosis
5
Aortic Stenosis -- left ventricular hypertrophy
expected -- commissures messy, fused together
6
Calcific Aortic Stenosis -- rigid leaflets
7
Congenital Bicuspid Aortic Valve
8
Bicuspid Aortic Valve with extensive
calcifications
9
Left is hypertrophied heart
10
Left ventricular hypertrophy with enlarged left
atrium due to increased L ventricular pressure
leading to Mitral valve incompetency
11
Mitral valve prolapse -- basophilic ground
substance in leaflets
12
Extremely large Mitral Valve
13
Edematous connective tissue of mitral valve
prolapse
14
Mitral valve parachutes back into atrium
enlarged L atrium w/ mild L ventricular
hypertrophy
15
Non-bacterial endocarditis -- granular, composed
of fibrin and platelets, associated with
hypercoaguable states including adenocarcinomas
16
Vegetations on Aortic and Mitral valves from
infective endocarditis -- alpha-hemolyticstrep
(50) or S. aureus (20)
17
Infective endocarditis -- granular
18
Infective endocarditis with ruptured chordae
tendineae
19
Infective endocarditis -- ruptured valve
20
Subacute endocarditis -- firmer than acute,
granular -- mitral valve
21
Dissected valve with vegetations
22
Shortened, fused chordae tendineae
23
Artificial valve - porcine with calcifications
24
Normal Artery
Int. elastic membrane
Musc. media
Adventia
25
Atherosclerotic atheroma -- fibrofatty plaque
with fibrous cap -- in intima
Fibrous cap
26
Aorta with fatty streaks
27
Aortic streaks around mouths of arteries -- Sudan
red stain
28
Coronary artery with fatty streak -- intimal
hyperplasia with foamy cells
29
Atheromatous plaque -- Masson trichrome stain --
lumen (L) narrowed with fibrous cap (F), about
60 occlusion
30
Fibrous plaques on left, nasty ulcerated
atheromas on right
31
Acute MI -- 7 - 10 days old, probable LAD
32
Infrarenal aortic aneurysm -- Most common
location
33
Renal Arteriole showing hyaline arteriosclerosis
34
Hyperplastic (onionskin) arteriosclerosis --
associated with malignant hypertension
laminations of SMC and redundant basement membrane
35
Polyarteritis nodosa -- inflammatory thickening
of wall
Segmental fibroid necrosis
Normal vessel
36
Wegeners Granulomatosis -- epitheloid and giant
cells C-ANCA
37
Temporal (Giant Cell) Arteritis -- can lead to
blindness, nodular, with granulomatous
inflammation
38
Buergers Disease -- thromboangitis obliterans --
associated with male smokers -- tibial and radial
aa with adjacent ischemia affecting nerves
leading to pain
39
Syphilitic Aortitis -- chronic lymp inflammation
-- in vaso vasorum (aorta nutrition), leads to
dilation of aortic root, aortic valve
insufficiency, and tree barking
40
Syphilitic Aortic Aneurysm
41
Dissecting Aneurysm -- intramural hematoma ()
42
Esophageal varices -- portal hypertension
43
Esophageal varices -- swollen veins in submucosa
44
Thrombosed vein -- in leg, pain, tenderness, and
fever