Dear Tim,

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Welcome
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(No Transcript)
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Dear Tim, as far as I know this is the first
patient treated with CAVH in the world. We
performed this treatment in Vicenza in 1984 and
the patient survived. After that we published the
first series of 4 newborns treated with CAVH
(Kidney International 1986) . You made a great
deal of progress since then and even more with
this meeting. Best Wishes
Claudio Ronco
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Time and Transition

• 1984-Roncos KI paper
• 1990-CAVH becomes more common
• 1993-CVVH with adapted machinery
• 1995-automated CVVH(D) machinery
• 1997-ultrafiltration controllers with automated
  machinery
• 1998-Acute Dialysis Quality Initiative (ADQI.net)
• 1999-Thermic controls with automated machinery

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Time and Transition

• 2000-1st International Conference on Pediatric
  Continuous Renal Replacement Therapy
• 2001-1st FDA approved Bicarbonate Based Dialysate
  (Normocarb)
• 2001-ppCRRT Registry establishment (Stu
  Goldstein)
• 2001-Goldstein data on FO and outcome
• 2002-Citrate anticoagulation
• 2002-PCRRT 2
• 2002-PEDCRRT list serve

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Time and Transition

• Gambro releases Prismasate
• 2003-DiCarlo data on early intervention in Bone
  Marrow Transplantation
• 2004-Foland data on FO and outcome
• 2004-Data emerging on Pharmacy Errors
• 2004-PCRRT 3
• 2005-KI paper from ppCRRT
• 2006 PCRRT-Zurich

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DIALYSIS MODALITY
Patients ()
Belsha et al., Pediatr Nephrol, 1995
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Pediatric Choice of RRT
on RRT/yr
Year of RRT
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Why has this become common?

• Work in vascular access
• Dedicated staff who is interested in these
  children
• Patients continue to be sicker then historically
• Automated machinery has made the care easier
• Anticoagulation protocols have made it easier

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CRRT Who does it?

• Outside of NA wide country variation of whom is
  responsible for this therapy
• Within NA
• USA 60 done by Nephrology but often
  determined by manpower
• Adult Nephrologists Adult Intensivists
• Pediatric Nephrologists lt Pediatric Intensivists
• Canada 50 done by Nephrology

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Who really does CRRT?

• Nursing staff of the
• Dialysis units- thank you
• Critical Care units- thank you
• Neonatal intensive Care units- thank you

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What is the purpose of this meeting?

• To bring together those in the field who deal
  with any modality of MOSF with RRT who are
  willing to listen and learn, to talk and to
  exchange
• There are no experts in this field!!
• If you quit learning then it is time to go home
• (actually he said get the hell out before you
  hurt someone!)
• Robert Vernier MD (U of Mn, retired)

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Thank you

• To those of you who helped make this meeting
  happen
• Faculty
• Carol Malone
• Program and Meeting planner-USA
• Katrin Burow
• Program and Meeting planner-Europe
• PCRRT Organizing committee
• PCRRT Foundation, Inc

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Who are the faculty?

• Oskar Baenziger, MD
• University Childrens Hospital, Zürich,
  Switzerland
• Klaus-Eugen Bonzel, MD
• University Childrens Hospital, Essen, Germany

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Who are the faculty?

• Patrick D. Brophy, MD, FRCPC
• C.S. Mott Childrens Hospital at the University
  of Michigan, Ann Arbor, Michigan, USA
• Timothy E. Bunchman, MD
• DeVos Childrens Hospital, Grand Rapids,
  Michigan, USA

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Who are the faculty?

• Ali Dodge-Khatami, MD, PhD
• University Childrens Hospital, Zürich,
  Switzerland
• Michel Fischbach, MD
• Hôpital de Hautepierre, Strasbourg, France

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Who are the faculty?

• Bernhard Frey, MD
• University Childrens Hospital, Zürich,
  Switzerland
• Andree V. Gardner
• DeVos Childrens Hospital, Grand Rapids,
  Michigan, USA

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Who are the faculty?

• John J. Gardner, RN
• DeVos Childrens Hospital, Grand Rapids,
  Michigan, USA
• Peter Gessler, MD
• University Childrens Hospital, Zürich,
  Switzerland

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Who are the faculty?

• Markus J. Kemper, MD
• University Childrens Hospital Eppendorf,
  Hamburg, Germany
• Ernst P. Leumann, MD
• University Childrens Hospital, Zürich,
  Switzerland

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Who are the faculty?

• Marco Maggiorini, MD
• University Hospital, Zürich, Switzerland
• Thomas J. Neuhaus, MD
• University Childrens Hospital, Zürich,
  Switzerland

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Who are the faculty?

• Ekkehard Ring, MD
• Medical University Graz, Graz, Austria

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Thanks to our Supporters-1

• Arrow International
• Baxter Health Care
• Dialysis Solution Inc
• Edwards Life Sciences
• Freseuius
• Gambro Hospal
• Janssen-Cilag

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Thanks to our Supporters-2

• Novo Nordisk
• Novartis
• Pfizer
• Roche
• Vicor
• Government of Zurich (city and county)
• Swiss parents association of children with kidney
  disease

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Who are the Audience

• 27 abstracts were submitted from 12 separate
  countries
• 50 make up of Nursing
• 45 physician
• 5 pharmacist

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A few requests

• Ask questions..
• we all learn
• Interact with others outside your program during
  the breaks, lunch
• Visit the booths
• learn what each machine, solution, and access can
  do for your program

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A few requests

• Fill out your evaluation cards and hand them into
  the desk
• CMEs and CEUs are available for those requesting

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Finally

• Have fun and open your mind
• This is a therapy that is still in development.
  The applications of these therapies are without
  boundaries
• If Carol Malone, Katrin Burow, Thomas Neuhaus,
  Oskar Baenziger or I can help you in any way,
  please do not hesitate to ask.

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Quote that I live by

• the smartest one in the room is the child