Irving Institute for Clinical and Translational Research

1

• Irving Institute for Clinical and Translational
  Research
• Harold Alan Pincus
• Mark Graham
• Zoon Naqvi
• Department of Psychiatry
• New York-PresbyterianHospital
• Center for Education Research and Evaluation
• College of Physicians and Surgeons
• Teachers College
• Columbia University

2
Internal Advisory Committee
External Advisory Committee
Irving Institute for Clinical and Translational
Science Director (PI), Co-Director Faculty,
Administration
Clinical and Translational Research Support Key
Functions (1-9)
9. Research Education, Training, And
Career Development
1. Development of Novel C/T Methodologies
2. Pilot and Collaborative C/T Studies
4. Design, Bio- Statistics, and
Clinical Research Ethics Group
3. Biomedical Informatics Group
K12
T32
K30
7. Community Engagement Group
5. Regulatory Knowledge and Support Group
6. PCIR Inpatient Outpatient
Research Subject Advocate
Students
Residents
Organic Synthesis
8. Translational Technologies and Resources
Research Nurses, PAs, NPs, Coordinators
Clinical Genetics
IRB
Clinical Trials Office
Biomarkers
Imaging
Botanical Analysis
Research Pharmacy
3
Irving Institute for Clinical and Translational
Research Key strategies for Multi/Interdisciplin
ary Research

• "Think Tank" to assist C/T investigators
• TRANSFORM - training/nurturing/mentoring/space
• Interdisciplinary pilot grants
• Irving Fellows
• Bringing C/T research to the community (and vice
  versa)
• Workflow optimization (micro/macro)
• Clinical research ethics
• Blending clinical trials and personalized
  medicine
• Novel trial and statistical designs and tools
• Information systems for multi/interdisciplinary
  research
• Organic synthesis and botanical analysis centers
• Multimodality imaging and other resources

4
Buckets of Evaluation

• Grant Reporting / Renewal
• Service Improvement
• Intrinsic Evaluation
• Transformation
• National Evaluation

5
Transformation of

• Scientist
• Institution
• Science
• Health Practice
• Community
• Other?

6
Logic Model Evaluation of Community Engagement
Resource (CBER)
Inputs
Activities
Outcomes (short/ int./ long)
Existing Resources More effective organization of
the many community-based research programs
existing at CUMC
Support from Participant and Clinical
Interactions Resource

• Pilot grant awards
• Placement of community members to IRB
• Decreased IRB processing time
• Participant satisfaction
• New Community based investigators

Develop A centralized communication platform
e.g. Newsletters Research Fairs Web sites TV
programs Columbia Research Resource
Center. Community Engagement Advisory
Board Integration of all community based
protocols into the electronic repository New
Educational programs on e.g. research
participation informed consent research ethics.
Innovations Enhanced CBER training for young CUMC
faculty. Foster Community Partnerships and
improved communications.
Support from Regulatory Knowledge Support
Resource
Support from Informatics
7
Logic Model (contd) Outcomes Evaluation
8
Qualitative and Quantitative Data

• Web data
• Request forms
• Surveys
• Structured Observations
• Interviews

9
Work Allocation
10
Evaluation Matrix
11
Target Population

• Trainees
• Faculty
• Mentors
• Resource Leaders
• Denominator?
• Core
• Diffusion
• Comparison
• Implications for National Evaluation