CTSA Imaging Working Group

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CTSA Imaging Working Group

• Coordinated by
• RSNA (Radiologic Society of North America)
• DTRI (Duke Translational Research Institute)

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Rationale for RSNA Interest and Involvement
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RSNA Strategic Plan Goals

• Conduct activities to meet the educational and
  continuing professional development needs of RSNA
  members.
• Promote high quality science and research in
  radiology, radiation oncology, and radiologic
  physics.
• Maintain the preeminence of the annual meeting as
  a scientific and educational forum.
• Pursue excellence in publications and
  communications to advance radiologic science and
  education.
• Foster productive relationships with other
  organizations and corporate entities for the
  purpose of strengthening radiology.
• Foster relationships with international
  physicians and societies in recognition of an
  increasingly international radiologic community.
• Govern and manage RSNA in an effective,
  efficient, and fiscally responsible manner.

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RSNA Strategic Plan Goals

• Conduct activities to meet the educational and
  continuing professional development needs of RSNA
  members.
• Promote high quality science and research in
  radiology, radiation oncology, and radiologic
  physics.
• Maintain the preeminence of the annual meeting as
  a scientific and educational forum.
• Pursue excellence in publications and
  communications to advance radiologic science and
  education.
• Foster productive relationships with other
  organizations and corporate entities for the
  purpose of strengthening radiology.
• Foster relationships with international
  physicians and societies in recognition of an
  increasingly international radiologic community.
• Govern and manage RSNA in an effective,
  efficient, and fiscally responsible manner.

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Goal 2 Promote high quality science and research
in radiology, radiation oncology, and radiologic
physics.

• 2.1 Facilitate successful applications for
  funding from NIH and other sources.
• 2.2 Increase awareness of cutting edge
  developments and research opportunities vital to
  the future of radiology.
• 2.3 Stimulate the pursuit of cutting edge
  developments and research opportunities vital to
  the future of radiology.
• 2.4 Identify, stimulate and support research
  opportunities in residency and fellowship
  training.
• 2.5 Enhance the readiness and capability of the
  radiologic community to conduct research.
• 2.6 Prepare professionals in radiologic sciences
  for an increasingly quantitative future.
• 2.7 Increase the Research and Education
  Foundation resources.

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Goal 2 Promote high quality science and research
in radiology, radiation oncology, and radiologic
physics.

• 2.1 Facilitate successful applications for
  funding from NIH and other sources.
• 2.2 Increase awareness of cutting edge
  developments and research opportunities vital to
  the future of radiology.
• 2.3 Stimulate the pursuit of cutting edge
  developments and research opportunities vital to
  the future of radiology.
• 2.4 Identify, stimulate and support research
  opportunities in residency and fellowship
  training.
• 2.5 Enhance the readiness and capability of the
  radiologic community to conduct research.
• 2.6 Prepare professionals in radiologic sciences
  for an increasingly quantitative future.
• 2.7 Increase the Research and Education
  Foundation resources.

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CTSAs and IRATs

• RSNA coordination of CTSA Imaging Working Group
  is modeled after AACI (American Association of
  Cancer Institutes) coordination of NCI-funded
  Image Response Assessment Teams (IRATs)
• Significant overlap of investigators in IRATs and
  imaging components of CTSAs

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How is it funded?

• RSNA provides administrative and logistical
  support from the operating budget of its
  Scientific Division, headed by Dr. Linda
  Bresolin.
• RSNA contracts with Duke University for a
  percentage of Dr. Sullivans time.
• Dr. Reynolds time is included as part of his
  duties as Project Leader of the Imaging Core
  under DTRI.

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Emory Center for Systems Imaging (CSI)
4 Pillar Themes
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Common themes among CTSA imaging programs

• Inventory both imaging resources and imaging
  trials
• Create an imaging Core or centralized imaging
  resource some virtual, some physical
• Increase accessibility to information, expertise
  (possibly consultative) and equipment related to
  imaging
• Utilize/Integrate imaging in translational
  research
• Increase knowledge of imaging biomarkers and
  their use as endpoints in clinical trials
• Implement or improve image storage and analysis
  PACS and analytical tools
• Develop mechanisms for data sharing
• Provide training in translational research to new
  and established investigators
• Develop innovations in imaging

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RSNA-Duke Role in Developing an Imaging Working
Group within the CTSA program

• Organizational meeting, Chicago, Nov 27, 2007
• Requests for regular conference calls, wiki,
  periodic meetings
• Conference call with NCRR NIBIB staff Jan 2008

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RSNA-Duke Role in Developing an Imaging Working
Group within the CTSA program

• Conference calls with grantees, Feb 12 Apr 11
  2008
• Requests for subcommittees on
• Core resources
• Imaging Informatics
• Clinical Trials
• Education
• Quantification

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• Participation in this Imaging Working Group and
  Subgroups is open to all interested people.
• (Modeled after the NCI-funded caBIG Workspaces).

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IWG Subcommittees in development

• Core Resources
• Brian Reynolds, PhD, Duke
• Imaging Informatics
• Brad Erickson, MD, PhD, Mayo
• Clinical Trials
• Gary Dorfman, MD, Cornell
• Education
• Katarzyna Macura, MD, PhD, Hopkins

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Core Resources Subcommittee

• Share information about organization, management,
  finances for core resources
• Promulgate best practices
• Provide support group for non-faculty-member
  Core Managers (e.g., career development issues,
  etc.)

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Imaging Informatics Project Group

• Goal Develop an inter-operable imaging
  informatics infrastructure that enables maximal
  sharing of image-derived data and information
  from research that can be widely deployed to CTSA
  sites, IRAT sites, Cancer Centers and other major
  research facilities employing medical imaging.
• Methods
• 1. Monthly (TBD) teleconferences in which
  participants discuss what and how to achieve goal
• 2. Participate in CTSA Informatics activities and
  Imaging Informatics activities in other venues
• 3. Establish task groups focused on components of
  the larger plan
• 4. Consider arranging/participating in a workshop
  on imaging informatics needs / available tools
  for research
• 5. Develop proposals and plans for prototypes /
  test installations

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Clinical Trials Subcommittee

• Develop UPICT (Uniform Protocols for Imaging in
  Clinical Trials)
• Help CTSA imaging groups establish procedures for
  imaging involvement in development of and review
  of clinical trial protocols at their institutions
• Develop a proposal for a multi-site demonstration
  project related to imaging in clinical trials
  (e.g., a validation study of an imaging
  biomarker).

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Education Subcommittee

• Inventory resources available to imagers and
  users of imaging to educate them about
  appropriate methodology for clinical trials.
• Develop educational activities or resources to
  fill gaps identified by above inventory.

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Future Plans

• Full conference calls q 2 mos
• Subgroup conference calls TBD, maybe monthly
• Face-to-face meetings
• October 2, 2008, Pentagon City, VA, all day (with
  ACRIN meeting)
• December 2, 2008, Chicago, 3 to 5 PM (with RSNA
  meeting)
• 2009, TBD, 1.5 days (with IRATs)
• Google group established
• Web site under development

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Future Plans

• Determine appropriate interactions with
  Translational Steering Committee, and other
  Steering Committees
• Determine appropriate interactions with other
  relevant subcommittees, task forces, etc.

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Questions?

• Thank you.