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Muscle Tissue

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I use these PowerPoint s in histology lectures that I give to first year medical students. Copy the s, or just the images into your own teaching media. ... – PowerPoint PPT presentation

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Title: Muscle Tissue


1
Stephen E. Fish, Ph.D. Mitchell L. Berk,
Ph.D. Marshall University J. C. E. School of
Medicine
2
Note to instructors I use these PowerPoint
slides in histology lectures that I give to first
year medical students. Copy the slides, or just
the images into your own teaching media. We all
know that teaching science often requires
compromises and simplification for specific
student populations, or the requirements of a
specific course. Please feel free to offer
suggestions for improvements, corrections, or
additional illustrations. I would be pleased to
hear from anyone who finds my work useful, and am
always willing to make it better. Also, the
images have been compressed to screen resolution
to keep PowerPoint file size down, and I can
provide them at any resolution. Contact me about
the illustrations and Mitchell L. Berk about the
photomicrographs. Stephen E. Fish,
Ph.D. Fish_at_Marshall.edu Berk_at_Marshall.edu
3
Introduction to Muscle
4
3 Muscle types Skeletal
  • Striated (but so is cardiac)
  • Voluntary (except in reflexes)
  • Strong, fast, discontinuous contractions

5
3 Muscle types Cardiac
  • Striated (but so is skeletal)
  • Always involuntary
  • Strong, intermediate speed, continuous repeated
    contractions

6
3 Muscle types Smooth
  • Not striated
  • Always involuntary
  • Weak, slow, can sustain continuous contraction

7
Definition of a muscle fiber
  • A skeletal muscle fiber is a single, long,
    multinucleated cell with flattened nuclei on the
    periphery
  • A cardiac muscle fiber is an indeterminate number
    of cells with 1 (occasionally 2) rounded nuclei
    that are joined end to end
  • A smooth muscle fiber is a single cell with a
    single speckled hotdog nucleus in the center

8
Connective tissue components of a skeletal muscle
  • Transfers pull to skeleton
  • Brings in vessels nerves
  • Type 1 collagen
  • Epi peri are dense irregular
  • Endo is loose irregular

9
Connective tissue component terminology of all 3
muscle types
10
Other components of muscle CT
11
Skeletal muscle
12
Skeletal muscle
Cross section
Longitudinal section
Who is this guy
What is this?
Notice striations on longitudinal sections
Notice texture on the cut ends of cross sections
13
Skeletal muscle CT (there is very little
epimysium on our slides)
Perimysium
Endomysium
14
Endomysium
Perimysium
Epimysium
15
Striations
Dark A bands Light I bands Z line in
your imaginoscope
What is this nucleus in the middle?
16
Bands are a feature of myofibrils within a fiber
17
Origin of bands lines
18
Detail you can see in EM photographs
19
Myosin motor heads make cross bridges between the
myosin 2 filament actin
20
Ca binds troponin to initiate contraction
21
T-tubules the sarcoplasmic reticulum
22
Motor units
23
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