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... of covalently linked amino acids. Polypeptides with 40 amino acids are called peptides ... Allows amino acid substitutions at specific sites in a protein ...
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Biodistribution of Protein Drugs Origin of Peptide Pharmaceuticals Therapy using protein hormones dates back to the 1920s Due to the Genomics Revolution cir. 1980 ...
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Enhancing Drug Bioavailability by Overcoming Intestinal Metabolism Dr. Basavaraj K. Nanjwade M.Pharm., Ph.D Professor of Pharmaceutics Department of Pharmaceutics
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Antiviral Agents Viruses Obligate intracellular parasites Consist of a core genome in a protein shell and some are surrounded by a lipoprotein lack a cell wall and ...
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Van der Waals Surface. Reentrant Surface. Accessible Surface ... Minimize covalent and noncovalent (van der Waals and coulombic) energies. Conclusions (Part I) ...
EPO-R EXISTS AS A PREFORMED DIMER. Livnah et al. Science 283: 990, 1999 ... Adenocarcinoma. Patients who had never smoked. EGFR MUTATIONS CONFERS DRUG SENSITIVITY ...
Pharmaceutical Biotechnology 4.The Drug development process Dr. Tarek El-Bashiti Assoc. Prof. of Biotechnology * * Protein mode of action and pharmacodynamics ...
Nucleic acid aptamers Aptamers: molecules that bind other molecules with good affinity and specificity Usually these are proteins . . . . But they can also be RNA or DNA.
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Pharmaceutical Biotechnology 4.The Drug development process Dr. Tarek El-Bashiti Assoc. Prof. of Biotechnology * 3. appropriate route and frequency of administration ...
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