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From the Pulitzer Prize-winning bestselling author of The Emperor of All Maladies a magnificent history of the gene and a response to the defining question of the future What becomes of being human when we learn to read and write our own genetic information Siddhartha Mukherjee has a written a biography of the gene as deft brilliant and illuminating as his extraordinarily successful biography of cancer Weaving science social history and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times Mukherjee animates the quest to understand human heredity and its surprising influence on our lives personalities identities fates and choices Throughout the narrative the story of Mukherjee s own family with its tragic and bewildering history of mental illness cuts like a bright red line reminding us of the many questions that hang over our ability to translate the science of genetics from the laboratory to the real world In superb prose and with an instinct for the dramatic scene he describes the centuries of research and experimentation from Aristotle and Pythagoras to Mendel and Darwin from Boveri and Morgan to Crick Watson and Franklin all the way through the revolutionary... twenty-first century innovators who mapped the human genome As The New Yorker said of The Emperor of All Maladies It s hard to think of many books for a general audience that have rendered any area of modern science and technology with such intelligence accessibility and compassion An extraordinary achievement Riveting revelatory and magisterial history of a scientific idea coming to life and an essential preparation for the moral complexity introduced by our ability to create or write the human genome The Gene is a must-read for everyone concerned about the definition and future of humanity This is the most crucial science of our time intimately explained by a master more
This 1 New York Times best-selling guide to decluttering your home from Japanese cleaning consultant Marie Kondo takes readers step-by-step through her revolutionary KonMari Method for simplifying organizing and storing Despite constant efforts to declutter your home do papers still accumulate like snowdrifts and clothes pile up like a tangled mess of noodles Japanese cleaning consultant Marie Kondo takes tidying to a whole new level promising that if you properly simplify and organize your home once you ll never have to do it again Most methods advocate a room-by-room or little-by-little approach which doom you to pick away at your piles of stuff forever The KonMari Method with its revolutionary category-by-category system leads to lasting results In fact none of Kondo s clients have lapsed and she still has a three-month waiting list With detailed guidance for determining which items in your house spark joy and which don t this international bestseller featuring Tokyo s newest lifestyle phenomenon will help you clear your clutter and enjoy the unique magic of a tidy home and the calm motivated mindset it can inspire
1 NEW YORK TIMES BESTSELLER For readers of Atul Gawande Andrew Solomon and Anne Lamott this inspiring exquisitely observed memoir finds hope and beauty in the face of insurmountable odds as an idealistic young neurosurgeon attempts to answer the question What makes a life worth living At the age of thirty-six on the verge of completing a decade s worth of training as a neurosurgeon Paul Kalanithi was diagnosed with stage IV lung cancer One day he was a doctor treating the dying and the next he was a patient struggling to live And just like that the future he and his wife had imagined evaporated When Breath Becomes Air chronicles Kalanithi s transformation from a na ve medical student possessed as he wrote by the question of what given that all organisms die makes a virtuous and meaningful life into a neurosurgeon at Stanford working in the brain the most critical place for human identity and finally into a patient and new father confronting his own mortality What makes life worth living in the face of death What do you do when the future no longer a ladder toward your goals in life flattens out into a perpetual present What does it mean to have a child to nurture a new life as another fades away These are some of the questions... Kalanithi wrestles with in this profoundly moving exquisitely observed memoir Paul Kalanithi died in March 2015 while working on this book yet his words live on as a guide and a gift to us all I began to realize that coming face to face with my own mortality in a sense had changed nothing and everything he wrote Seven words from Samuel Beckett began to repeat in my head I can t go on I ll go on When Breath Becomes Air is an unforgettable life-affirming reflection on the challenge of facing death and on the relationship between doctor and patient from a brilliant writer who became both Praise for When Breath Becomes Air I guarantee that finishing this book and then forgetting about it is simply not an option Part of this book s tremendous impact comes from the obvious fact that its author was such a brilliant polymath And part comes from the way he conveys what happened to him passionately working and striving deferring gratification waiting to live learning to die so well None of it is maudlin Nothing is exaggerated As he wrote to a friend It s just tragic enough and just imaginable enough And just important enough to be unmissable Janet Maslin The New York Times An emotional investment well worth making a moving and thoughtful memoir of family medicine and literature It is despite its grim undertone accidentally inspiring The Washington Post Possesses the gravity and wisdom of an ancient Greek tragedy Kalanithi delivers his chronicle in austere beautiful prose The book brims with insightful reflections on mortality that are especially poignant coming from a trained physician familiar with what lies ahead The Boston Globe Devastating and spectacular Kalanithi is so likeable so relatable and so humble that you become immersed in his world and forget where it s all heading USA Today It s Kalanithi s unsentimental approach that makes When Breath Becomes Air so original and so devastating Its only fault is that the book like his life ends much too early Entertainment Weekly Split my head open with its beauty Cheryl Strayedmore
For more than sixty years the rock-solid time-tested advice in this book has carried thousands of now famous people up the ladder of success in their business and personal lives Now this previously revised and updated bestseller is available in trade paperback for the first time to help you achieve your maximum potential throughout the next century Learn Three fundamental techniques in handling people The six ways to make people like you The twelve ways to win people to you way of thinking The nine ways to change people without arousing resentment
A devastating inside look at the dark side of Congress as revealed by one of its own No wonder Congressman X wants to remain anonymous for fear of retribution His admissions are deeply disturbing Most of my colleagues are dishonest career politicians who revel in the power and special-interest money that s lavished upon them My main job is to keep my job to get reelected It takes precedence over everything Voters are incredibly ignorant and know little about our form of government and how it works It s far easier than you think to manipulate a nation of naive self-absorbed sheep who crave instant gratification Fundraising is so time consuming I seldom read any bills I vote on Like many of my colleagues I don t know how the legislation will be implemented or what it ll cost We spend money we don t have and blithely mortgage the future with a wink and a nod Screw the next generation It s about getting credit now lookin good for the upcoming election
New York Times Bestseller I would recommend this book to anyone interested in a fun engaging look at early human history you ll have a hard time putting it down --Bill Gates Thank God someone finally wrote this exact book --Sebastian JungerFrom a renowned historian comes a groundbreaking narrative of humanity s creation and evolution a 1 international bestseller that explores the ways in which biology and history have defined us and enhanced our understanding of what it means to be human One hundred thousand years ago at least six different species of humans inhabited Earth Yet today there is only one homo sapiens What happened to the others And what may happen to us Most books about the history of humanity pursue either a historical or a biological approach but Dr Yuval Noah Harari breaks the mold with this highly original book that begins about 70 000 years ago with the appearance of modern cognition From examining the role evolving humans have played in the global ecosystem to charting the rise of empires Sapiens integrates history and science to reconsider accepted narratives connect past developments with contemporary concerns and examine specific events within the context of larger ideas Dr Harari also compels us to look... ahead because over the last few decades humans have begun to bend laws of natural selection that have governed life for the past four billion years We are acquiring the ability to design not only the world around us but also ourselves Where is this leading us and what do we want to become Featuring 27 photographs 6 maps and 25 illustrations diagrams this provocative and insightful work is sure to spark debate and is essential reading for aficionados of Jared Diamond James Gleick Matt Ridley Robert Wright and Sharon Moalem more
1 NEW YORK TIMES BESTSELLER NATIONAL BOOK AWARD WINNER NAACP IMAGE AWARD WINNER PULITZER PRIZE FINALIST NATIONAL BOOK CRITICS CIRCLE AWARD FINALIST NAMED ONE OF THE TEN BEST BOOKS OF THE YEAR BY The New York Times Book Review O The Oprah Magazine The Washington Post People Entertainment Weekly Vogue Los Angeles Times San Francisco Chronicle Chicago Tribune New York Newsday Library Journal Publishers WeeklyHailed by Toni Morrison as required reading a bold and personal literary exploration of America s racial history by the single best writer on the subject of race in the United States The New York Observer This is your country this is your world this is your body and you must find some way to live within the all of it In a profound work that pivots from the biggest questions about American history and ideals to the most intimate concerns of a father for his son Ta-Nehisi Coates offers a powerful new framework for understanding our nation s history and current crisis Americans have built an empire on the idea of race a falsehood that damages us all but falls most heavily on the bodies of black women and men bodies exploited through slavery and segregation and today threatened locked up and murdered out of all proportion What is... it like to inhabit a black body and find a way to live within it And how can we all honestly reckon with this fraught history and free ourselves from its burden Between the World and Me is Ta-Nehisi Coates s attempt to answer these questions in a letter to his adolescent son Coates shares with his son and readers the story of his awakening to the truth about his place in the world through a series of revelatory experiences from Howard University to Civil War battlefields from the South Side of Chicago to Paris from his childhood home to the living rooms of mothers whose children s lives were taken as American plunder Beautifully woven from personal narrative reimagined history and fresh emotionally charged reportage Between the World and Me clearly illuminates the past bracingly confronts our present and offers a transcendent vision for a way forward Praise for Between the World and Me I ve been wondering who might fill the intellectual void that plagued me after James Baldwin died Clearly it is Ta-Nehisi Coates The language of Between the World and Me like Coates s journey is visceral eloquent and beautifully redemptive And its examination of the hazards and hopes of black male life is as profound as it is revelatory Toni Morrison Powerful and passionate profoundly moving a searing meditation on what it means to be black in America today Michiko Kakutani The New York Times Really powerful and emotional John Legend The Wall Street Journal Extraordinary David Remnick The New Yorker Brilliant a mature writer entirely consumed by a momentous subject and working at the extreme of his considerable powers The Washington Post An eloquent blend of history reportage and memoir The Boston Globe Coates speaks resolutely and vividly to all of black America Los Angeles Times A work that s both titanic and timely the latest essential reading in America s social canon Entertainment Weeklymore
In Being Mortal bestselling author Atul Gawande tackles the hardest challenge of his profession how medicine can not only improve life but also the process of its endingMedicine has triumphed in modern times transforming birth injury and infectious disease from harrowing to manageable But in the inevitable condition of aging and death the goals of medicine seem too frequently to run counter to the interest of the human spirit Nursing homes preoccupied with safety pin patients into railed beds and wheelchairs Hospitals isolate the dying checking for vital signs long after the goals of cure have become moot Doctors committed to extending life continue to carry out devastating procedures that in the end extend suffering Gawande a practicing surgeon addresses his profession s ultimate limitation arguing that quality of life is the desired goal for patients and families Gawande offers examples of freer more socially fulfilling models for assisting the infirm and dependent elderly and he explores the varieties of hospice care to demonstrate that a person s last weeks or months may be rich and dignified Full of eye-opening research and riveting storytelling Being Mortal asserts that medicine can comfort and enhance our experience even... to the end providing not only a good life but also a good end more
Best-selling author Radhanath Swami inspires readers once more in this long-awaited follow-up to The Journey Home Autobiography of an American Swami Intimate stories from his decades of experience as a guru illustrate the basic tenets of bhakti yoga and illuminating references to Western religions and ideologies make this ancient philosophy more accessible than ever The Journey Within invites readers from all backgrounds to delve into their hearts and discover the simple truths that unite us all World-renowned spiritual leader Radhanath Swami draws from his path toward enlightenment and his personal experiences to demystify the ancient devotional path of bhakti capturing its essence and explaining its simple principles for balancing our lives His down-to-earth writing simplifies spiritual concepts and answers timeless questions in a heartfelt narrative that brings this sacred philosophy beautifully to life What is love What is the soul Who is God How can we live in the physical world without losing touch with the spiritual In concise and approachable language Radhanath Swami sheds light on how to answer these vital questions and offers solution to life s dilemmas with the simplest of resources Begin your own journey within and... uncover the path of self-discovery and transformation more
In The Four Agreements bestselling author don Miguel Ruiz reveals the source of self-limiting beliefs that rob us of joy and create needless suffering Based on ancient Toltec wisdom The Four Agreements offer a powerful code of conduct that can rapidly transform our lives to a new experience of freedom true happiness and love A New York Times bestseller for over 8 years Over 6 million copies sold in the U S Translated into 40 languages worldwide
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